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Peptide record

TPDB14152

Antibacterial Anticancer Antifungal Antiparasitic standard
17 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14152
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, and Peptipedia, with an available 3D structural model.
Sequence
FFSLIPSLIGGLVSAIK
Physicochemical Analysis
C86H140N18O21
RNDCEQHMTWY
ILS
1762.17
10.10
1
0
10
+1
-3.12
1.635
160.59
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
3
I
3
L
1
K
0
M
2
F
1
P
3
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 3 L: 3 K: 1 M: 0 F: 2 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C86H140N18O21
1762.17
10.10
+1
-3.12
1.635
Evidence Records 27 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>400 µg/mL

Target

P.aeruginosa DSM 50071

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumanni
Evidence 2 Activity

Activity

MIC
Antibacterial
200 µg/mL

Target

E.coli DSM 787

Source & Reference

dbAMP DRAMP

Other

active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S.
Evidence 3 Activity

Activity

MIC
Antibacterial
>400 µg/mL

Target

K.pneumoniae ATCC BAA 1705

Source & Reference

dbAMP DRAMP

Other

active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermi
Evidence 4 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

A. baumannii DSM 30008

Source & Reference

dbAMP DRAMP

Other

>400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecal
Evidence 5 Activity

Activity

MIC
Antibacterial
25 µg/mL

Target

Staphylococcus aureus ATCC 43300

Source & Reference

dbAMP DRAMP

Other

ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faeci
Evidence 6 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Staphylococcus epidermidis DSM 28319

Source & Reference

dbAMP DRAMP

Other

>400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. diffi
Evidence 7 Activity

Activity

MIC
Antibacterial
100 µg/mL

Target

Enterococcus faecalis MF 06036

Source & Reference

dbAMP DRAMP

Other

00 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 5
Evidence 8 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

E. faecium NCTC 12201

Source & Reference

dbAMP DRAMP

Other

5 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 50 ug/ml) ( Mechkarska et al., 2023 ).
Evidence 9 Activity

Activity

MIC
Antibacterial
50 µg/mL

Target

Clostridioides difficile DSM 27147 or ATCC BAA 1382

Source & Reference

dbAMP DRAMP

Other

0 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 50 ug/ml) ( Mechkarska et al., 2023 ).
Evidence 10 Activity

Activity

MIC
Antifungal
>400 µg/mL

Target

P.aeruginosa DSM 50071

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumanni
Evidence 11 Activity

Activity

MIC
Antifungal
200 µg/mL

Target

E.coli DSM 787

Source & Reference

dbAMP DRAMP

Other

active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S.
Evidence 12 Activity

Activity

MIC
Antifungal
>400 µg/mL

Target

K.pneumoniae ATCC BAA 1705

Source & Reference

dbAMP DRAMP

Other

active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermi
Evidence 13 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

A. baumannii DSM 30008

Source & Reference

dbAMP DRAMP

Other

>400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecal
Evidence 14 Activity

Activity

MIC
Antifungal
25 µg/mL

Target

Staphylococcus aureus ATCC 43300

Source & Reference

dbAMP DRAMP

Other

ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faeci
Evidence 15 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Staphylococcus epidermidis DSM 28319

Source & Reference

dbAMP DRAMP

Other

>400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. diffi
Evidence 16 Activity

Activity

MIC
Antifungal
100 µg/mL

Target

Enterococcus faecalis MF 06036

Source & Reference

dbAMP DRAMP

Other

00 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 5
Evidence 17 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

E. faecium NCTC 12201

Source & Reference

dbAMP DRAMP

Other

5 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 50 ug/ml) ( Mechkarska et al., 2023 ).
Evidence 18 Activity

Activity

MIC
Antifungal
50 µg/mL

Target

Clostridioides difficile DSM 27147 or ATCC BAA 1382

Source & Reference

dbAMP DRAMP

Other

0 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 50 ug/ml) ( Mechkarska et al., 2023 ).
Evidence 19 Activity

Activity

MIC
Antiparasitic
>400 µg/mL

Target

P.aeruginosa DSM 50071

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumanni
Evidence 20 Activity

Activity

MIC
Antiparasitic
200 µg/mL

Target

E.coli DSM 787

Source & Reference

DRAMP

Other

active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S.
Evidence 21 Activity

Activity

MIC
Antiparasitic
>400 µg/mL

Target

K.pneumoniae ATCC BAA 1705

Source & Reference

DRAMP

Other

active against P.aeruginosa DSM 50071 (MIC >400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermi
Evidence 22 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

A. baumannii DSM 30008

Source & Reference

DRAMP

Other

>400 ug/ml), E.coli DSM 787 (MIC 200 ug/ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecal
Evidence 23 Activity

Activity

MIC
Antiparasitic
25 µg/mL

Target

Staphylococcus aureus ATCC 43300

Source & Reference

DRAMP

Other

ml), K.pneumoniae ATCC BAA 1705 (MIC >400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faeci
Evidence 24 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Staphylococcus epidermidis DSM 28319

Source & Reference

DRAMP

Other

>400 ug/ml), A. baumannii DSM 30008 (MIC 100 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. diffi
Evidence 25 Activity

Activity

MIC
Antiparasitic
100 µg/mL

Target

Enterococcus faecalis MF 06036

Source & Reference

DRAMP

Other

00 ug/ml), S. aureus ATCC 43300 (MIC 25 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 5
Evidence 26 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

E. faecium NCTC 12201

Source & Reference

DRAMP

Other

5 ug/ml), S. epidermidis DSM 28319 (MIC 100 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 50 ug/ml) ( Mechkarska et al., 2023 ).
Evidence 27 Activity

Activity

MIC
Antiparasitic
50 µg/mL

Target

Clostridioides difficile DSM 27147 or ATCC BAA 1382

Source & Reference

DRAMP

Other

0 ug/ml), E. faecalis MF 06036 (MIC 100 ug/ml), E. faecium NCTC 12201 (MIC 50 ug/ml), and C. difficile DSM 27147 or ATCC BAA 1382 (MIC 50 ug/ml) ( Mechkarska et al., 2023 ).