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Peptide record

TPDB14146

Antibacterial Antifungal Antiparasitic Antiviral standard

55 amino acids

3D PDB MODEL

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TPDB ID TPDB14146

Activity

Antibacterial Antifungal Antiparasitic Antiviral

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP DRAMP Peptipedia Antifungipept dbAMP 3.0 i2APP

Sequence_Type

standard

Has_Modification No

Description A 55-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.

Sequence

FFGRLKSMWRGARGGLKAYKYQKDMAKMNKRYGPNWQQGGGQEPPADAQANDQPP

FASTA

>TPDB14146|Antibacterial;Antifungal;Antiparasitic;Antiviral|length=55
FFGRLKSMWRGARGGLKAYKYQKDMAKMNKRYGPNWQQGGGQEPPADAQANDQPP

Formula C275H418N84O77S3

Absent Amino Acids CHITV

Common Amino Acids G

Mass 6229.04

PI 10.48

Basic Residues 10

Acidic Residues 4

Hydrophobic Residues 18

Net Charge +6

Boman Index 10.48

Hydrophobicity -1.362

Aliphatic Index 25.09

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 15470

Absorbance 280nm 248.35

Polar Residues 13

number

Amino Acid Distribution

A: 6 R: 4 N: 3 D: 3 C: 0 E: 1 Q: 6 G: 8 H: 0 I: 0 L: 2 K: 6 M: 3 F: 2 P: 5 S: 1 T: 0 W: 2 Y: 3 V: 0

Length

Formula

C275H418N84O77S3

Mass

6229.04

10.48

Net Charge

Boman Index

10.48

Hydrophobicity

-1.362

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 32.11 µM

Target

Target Organism L. garvieae

Source & Reference

Database Source dbAMP DRAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8.03 µM

Target

Target Organism V. anguillarum

Source & Reference

Database Source dbAMP DRAMP

Other

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (MIC >32.11 uM), S-aureus (MIC

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 32.11 µM

Target

Target Organism L. garvieae

Source & Reference

Database Source dbAMP DRAMP Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antifungal

Activity Measurement 8.03 µM

Target

Target Organism V. anguillarum

Source & Reference

Database Source dbAMP DRAMP Antifungipept

Other

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (MIC >32.11 uM), S-aureus (MIC

Evidence 5 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 32.11 µM

Target

Target Organism L. garvieae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiparasitic	DRAMP antiparasitic activity supported by activity records against parasitic targets. dbAMP 3.0 classified under the Anti-parasitic function class.

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (

Evidence 6 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiparasitic

Activity Measurement 8.03 µM

Target

Target Organism V. anguillarum

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (MIC >32.11 uM), S-aureus (MIC

Evidence 7 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 32.11 µM

Target

Target Organism L. garvieae

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Source Activity Label	Source Definition
Antiviral	DRAMP antiviral activity supported by activity records against viral targets. dbAMP 3.0 classified under the Anti-viral function class.

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (

Evidence 8 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antiviral

Activity Measurement 8.03 µM

Target

Target Organism V. anguillarum

Source & Reference

Database Source dbAMP 3.0 DRAMP

Other

Evidence Text

fish pathogens S-iniae (MIC >32.11 uM), L. garvieae (MIC 32.11 uM), V. anguillarum (MIC 8.03 uM), A-salmonicida (MIC>32.11 uM), human pathogens E-faecalis (MIC >32.11 uM), S-aureus (MIC