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Peptide record

TPDB14078

Antibacterial Antifungal standard
66 amino acids
Basic Information
3D PDB MODEL
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TPDB14078
Antibacterial Antifungal
Anti-infective peptides
dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 66-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
DSYKKIDCGGACAARCRLSSRPRLCHRACGTCCARCNCVPPGTSGNTETCPCYASLTTHGNKRKCP
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C280H464N98O89S12
QMFW
C
7012.09
8.60
13
3
13
+8
2.38
-0.527
37.12
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
3730
0.53
28
Residue Composition
number
6
A
7
R
3
N
2
D
12
C
1
E
0
Q
6
G
2
H
1
I
3
L
4
K
0
M
0
F
5
P
5
S
6
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 6 R: 7 N: 3 D: 2 C: 12 E: 1 Q: 0 G: 6 H: 2 I: 1 L: 3 K: 4 M: 0 F: 0 P: 5 S: 5 T: 6 W: 0 Y: 2 V: 1
Chemical Descriptors
66 reviewed residue count
C280H464N98O89S12 sequence-only estimate (linear, free termini)
7012.09 sequence-only estimate (linear, free termini)
8.60 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
2.38 sequence-only estimate (linear, free termini)
-0.527 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli, B. subtilis, and S. cerevisiae (Brewer's yeast) ( PeerJ 2016 ).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli, B. subtilis, and S. cerevisiae (Brewer's yeast) ( PeerJ 2016 ).