Back to search

Peptide record

TPDB14042

Antibacterial Anticancer Antifungal Antiparasitic standard
86 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB14042
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifp Antifungipept
standard
No
A 86-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
DHHHDHGHDDHEHEELTLEKIKEKIKDYADKTPVDQLTERVQAGRDYLLGKGARPSHLPARVDRHLSKLTAAEKQELADYLLTFLH
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C438H688N132O136
NCMW
L
9979.08
6.03
23
18
28
-4
2.83
-1.070
81.74
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
4470
0.45
13
Residue Composition
number
7
A
5
R
0
N
10
D
0
C
8
E
3
Q
4
G
10
H
2
I
12
L
8
K
0
M
1
F
3
P
2
S
5
T
0
W
3
Y
3
V
Amino Acid Distribution
A: 7 R: 5 N: 0 D: 10 C: 0 E: 8 Q: 3 G: 4 H: 10 I: 2 L: 12 K: 8 M: 0 F: 1 P: 3 S: 2 T: 5 W: 0 Y: 3 V: 3
Chemical Descriptors
86 reviewed residue count
C438H688N132O136 sequence-only estimate (linear, free termini)
9979.08 sequence-only estimate (linear, free termini)
6.03 sequence-only estimate (linear, free termini)
-4 sequence-only estimate (linear, free termini)
2.83 sequence-only estimate (linear, free termini)
-1.070 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against M. luteus (MIC 250–500 nM). Updated 10/2016.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against M. luteus (MIC 250–500 nM). Updated 10/2016.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against M. luteus (MIC 250–500 nM). Updated 10/2016.