TPDB

3D PDB MODEL

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TPDB ID TPDB14041

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 517-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

DGVCRNRRQCNKEVCGSSYDVAIVGAGPGGANSAYMLRESGLDIAVFEYSDRVGGRLFTYQLPNTPDVNLEIGGMRFIEGAMHRLWKVISELGLTPKVFKEGFGKEGRQRFYLRGQSLTKKQVKSGDVPYDLSPEEKANQGRLVEYYLEKLTGLQLNGGPLKREVALKLTVPDGRFLYDLTFDEALDLVASPEGKEFARDTHVFTSEVTLDASAISIFDDHLGEDYYGSEIYTLEEGMSSVPQGLLQTFLDAAKSNEFFPNNHLKALRRRTNGQYVLYFEPTTSKDGQTTINYLEPLKVVCAQRVILAMPVYALRQLDWSQLRNDRATQAYRAVRPMPASKVFMTFDQPWWLQNERKSWVTKSDALFSQMYDWQKSEASGDYILIASYADGLKAQYLRELKNQGEDIPGSDPGYNQVTVPLKDAILEHLTEAYGVERDSIPEPVTAASQFWTDYPFGCGWITWRAGYHFDDVISTMRRPSLKDEVYVVGSDYSWGLISSWIEGALETSENVINDYFL

FASTA

>TPDB14041|Antibacterial|length=517
DGVCRNRRQCNKEVCGSSYDVAIVGAGPGGANSAYMLRESGLDIAVFEYSDRVGGRLFTYQLPNTPDVNLEIGGMRFIEGAMHRLWKVISELGLTPKVFKEGFGKEGRQRFYLRGQSLTKKQVKSGDVPYDLSPEEKANQGRLVEYYLEKLTGLQLNGGPLKREVALKLTVPDGRFLYDLTFDEALDLVASPEGKEFARDTHVFTSEVTLDASAISIFDDHLGEDYYGSEIYTLEEGMSSVPQGLLQTFLDAAKSNEFFPNNHLKALRRRTNGQYVLYFEPTTSKDGQTTINYLEPLKVVCAQRVILAMPVYALRQLDWSQLRNDRATQAYRAVRPMPASKVFMTFDQPWWLQNERKSWVTKSDALFSQMYDWQKSEASGDYILIASYADGLKAQYLRELKNQGEDIPGSDPGYNQVTVPLKDAILEHLTEAYGVERDSIPEPVTAASQFWTDYPFGCGWITWRAGYHFDDVISTMRRPSLKDEVYVVGSDYSWGLISSWIEGALETSENVINDYFL

Formula C2627H4018N696O792S14

Absent Amino Acids

Common Amino Acids L

Mass 58471.83

PI 4.85

Basic Residues 61

Acidic Residues 71

Hydrophobic Residues 210

Net Charge -16

Boman Index 98.27

Hydrophobicity -0.406

Aliphatic Index 79.77

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 102470

Absorbance 280nm 175.25

Polar Residues 137

number

34

A

30

R

18

N

35

D

5

C

36

E

23

Q

42

G

6

H

20

I

51

L

25

K

9

M

22

F

24

P

36

S

27

T

11

W

28

Y

35

V

Amino Acid Distribution

A: 34 R: 30 N: 18 D: 35 C: 5 E: 36 Q: 23 G: 42 H: 6 I: 20 L: 51 K: 25 M: 9 F: 22 P: 24 S: 36 T: 27 W: 11 Y: 28 V: 35

Length

517

Formula

C2627H4018N696O792S14

Mass

58471.83

PI

4.85

Net Charge

-16

Boman Index

98.27

Hydrophobicity

-0.406

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.