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Peptide record

TPDB14028

Antibacterial Antifungal standard
59 amino acids
Basic Information
3D PDB MODEL
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TPDB14028
Antibacterial Antifungal
Anti-infective peptides
dbAMP Peptipedia Antifungipept
standard
No
A 59-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
DCYEDWSRCTPGTSFLTGILWKDCHSRCKELGHRGGRCVDSPSKHCPGVLKNNKQCHCY
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C284H437N89O85S8
AM
C
6714.62
8.10
13
6
12
+3
2.41
-0.824
42.88
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
14480
2.16
21
Residue Composition
number
0
A
4
R
2
N
4
D
8
C
2
E
1
Q
6
G
4
H
1
I
4
L
5
K
0
M
1
F
3
P
5
S
3
T
2
W
2
Y
2
V
Amino Acid Distribution
A: 0 R: 4 N: 2 D: 4 C: 8 E: 2 Q: 1 G: 6 H: 4 I: 1 L: 4 K: 5 M: 0 F: 1 P: 3 S: 5 T: 3 W: 2 Y: 2 V: 2
Chemical Descriptors
59 reviewed residue count
C284H437N89O85S8 sequence-only estimate (linear, free termini)
6714.62 sequence-only estimate (linear, free termini)
8.10 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
2.41 sequence-only estimate (linear, free termini)
-0.824 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against S. aureus.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against S. aureus.