TPDB

3D PDB MODEL

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TPDB ID TPDB14024

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 188-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

DAHGAVTLNTDGTSGAVVKVPIAGSDKNIVSAIGSVDLTDRLKVGAATAGLAIDNVNGHGASITDTHIPGFGDKLTAAGKINLIHNDNHDLTANAFATRNMPSIPLVPDFNTVGGGIDYMFKDKIGASASVAHTDLINRNDYSLGGKLNLFKTPDTSVDFNAGWKKFDTPVINSNWEPNFGFSLSKYF

FASTA

>TPDB14024|Antibacterial|length=188
DAHGAVTLNTDGTSGAVVKVPIAGSDKNIVSAIGSVDLTDRLKVGAATAGLAIDNVNGHGASITDTHIPGFGDKLTAAGKINLIHNDNHDLTANAFATRNMPSIPLVPDFNTVGGGIDYMFKDKIGASASVAHTDLINRNDYSLGGKLNLFKTPDTSVDFNAGWKKFDTPVINSNWEPNFGFSLSKYF

Formula C877H1362N240O275S2

Absent Amino Acids CQ

Common Amino Acids G

Mass 19732.02

PI 5.78

Basic Residues 21

Acidic Residues 19

Hydrophobic Residues 75

Net Charge -3

Boman Index 27.05

Hydrophobicity -0.130

Aliphatic Index 84.10

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour

Extinction Coefficient Cystines 15470

Absorbance 280nm 78.40

Polar Residues 48

number

19

A

3

R

17

N

18

D

0

C

1

E

0

Q

20

G

6

H

13

I

13

L

12

K

2

M

10

F

8

P

13

S

15

T

2

W

3

Y

13

V

Amino Acid Distribution

A: 19 R: 3 N: 17 D: 18 C: 0 E: 1 Q: 0 G: 20 H: 6 I: 13 L: 13 K: 12 M: 2 F: 10 P: 8 S: 13 T: 15 W: 2 Y: 3 V: 13

Length

188

Formula

C877H1362N240O275S2

Mass

19732.02

PI

5.78

Net Charge

-3

Boman Index

27.05

Hydrophobicity

-0.130

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.