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Peptide record

TPDB13991

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
51 amino acids
Basic Information
3D PDB MODEL
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TPDB13991
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP DRAMP Peptipedia ACP740 _ACP240 Antifungipept CAFPdb AVPpred-BWR dbAMP 3.0
standard
No
A 51-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, DRAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
ATYDGKCYKKDNICKYKAQSGKTAICKCYVKVCPRDGAKCEFDSYKGKCYC
Physicochemical Analysis
C250H393N67O74S8
HLMW
K
5777.76
8.88
12
5
15
+7
10.82
-0.755
34.51
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
9440
163.39
20
Residue Composition
number
4
A
1
R
1
N
4
D
8
C
1
E
1
Q
4
G
0
H
2
I
0
L
11
K
0
M
1
F
1
P
2
S
2
T
0
W
6
Y
2
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 4 C: 8 E: 1 Q: 1 G: 4 H: 0 I: 2 L: 0 K: 11 M: 0 F: 1 P: 1 S: 2 T: 2 W: 0 Y: 6 V: 2
Chemical Descriptors
51
C250H393N67O74S8
5777.76
8.88
+7
10.82
-0.755
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Inhibition zone: Inhibited A. niger (11 mm), F. solani (15 mm), and F. oxysporum (12 mm) using 50 ul of 200 ug/ml. This basic, Cys-rich antifungal peptide is also active against bacteria, including S. aureus (11-19 mm), B. cereus (15-22 mm), M. luteus (12-18 mm), E. faecalis (10-13 mm), E. coli (12-16 mm), P. aeruginosa and K.pneumonia (0 mm) treated at 50 to 200 ug/ml.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Inhibition zone: Inhibited A. niger (11 mm), F. solani (15 mm), and F. oxysporum (12 mm) using 50 ul of 200 ug/ml. This basic, Cys-rich antifungal peptide is also active against bacteria, including S. aureus (11-19 mm), B. cereus (15-22 mm), M. luteus (12-18 mm), E. faecalis (10-13 mm), E. coli (12-16 mm), P. aeruginosa and K.pneumonia (0 mm) treated at 50 to 200 ug/ml.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Inhibition zone: Inhibited A. niger (11 mm), F. solani (15 mm), and F. oxysporum (12 mm) using 50 ul of 200 ug/ml. This basic, Cys-rich antifungal peptide is also active against bacteria, including S. aureus (11-19 mm), B. cereus (15-22 mm), M. luteus (12-18 mm), E. faecalis (10-13 mm), E. coli (12-16 mm), P. aeruginosa and K.pneumonia (0 mm) treated at 50 to 200 ug/ml.
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0 DRAMP

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Inhibition zone: Inhibited A. niger (11 mm), F. solani (15 mm), and F. oxysporum (12 mm) using 50 ul of 200 ug/ml. This basic, Cys-rich antifungal peptide is also active against bacteria, including S. aureus (11-19 mm), B. cereus (15-22 mm), M. luteus (12-18 mm), E. faecalis (10-13 mm), E. coli (12-16 mm), P. aeruginosa and K.pneumonia (0 mm) treated at 50 to 200 ug/ml.