TPDB

3D PDB MODEL

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TPDB ID TPDB13989

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

ATTHTVKPGESVWAISNKYGISIAKLKSLNNLTSNLIFPNQVLKVSGSSNSTSNSSRPSTNSGGGSYYTVQAGDSLSLIASKYGTTYQNIMRLNGLNNFFIYPGQKLKVSGTASSSNAASNSSRPSTNSGGGSYYTVQAGDSLSLIASKYGTTYQKIMSLNGLNNFFIYPGQKLKVTGNASTNSGSATTTNRGYNTPVFSHQNLYTWGQCTYHVFNRRAEIGKGISTYWWNANNWDNAAAADGYTIDNRPTVGSI

FASTA

>TPDB13989|Antibacterial|length=255
ATTHTVKPGESVWAISNKYGISIAKLKSLNNLTSNLIFPNQVLKVSGSSNSTSNSSRPSTNSGGGSYYTVQAGDSLSLIASKYGTTYQNIMRLNGLNNFFIYPGQKLKVSGTASSSNAASNSSRPSTNSGGGSYYTVQAGDSLSLIASKYGTTYQKIMSLNGLNNFFIYPGQKLKVTGNASTNSGSATTTNRGYNTPVFSHQNLYTWGQCTYHVFNRRAEIGKGISTYWWNANNWDNAAAADGYTIDNRPTVGSI

Formula C1199H1846N338O387S3

Absent Amino Acids

Common Amino Acids S

Mass 27284.06

PI 10.05

Basic Residues 23

Acidic Residues 7

Hydrophobic Residues 89

Net Charge +13

Boman Index 12.82

Hydrophobicity -0.460

Aliphatic Index 65.45

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 51340

Absorbance 280nm 188.17

Polar Residues 118

number

18

A

7

R

29

N

5

D

1

C

2

E

9

Q

26

G

3

H

14

I

16

L

13

K

2

M

7

F

8

P

38

S

25

T

5

W

16

Y

11

V

Amino Acid Distribution

A: 18 R: 7 N: 29 D: 5 C: 1 E: 2 Q: 9 G: 26 H: 3 I: 14 L: 16 K: 13 M: 2 F: 7 P: 8 S: 38 T: 25 W: 5 Y: 16 V: 11

Length

255

Formula

C1199H1846N338O387S3

Mass

27284.06

PI

10.05

Net Charge

+13

Boman Index

12.82

Hydrophobicity

-0.460

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.