TPDB

3D PDB MODEL

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TPDB ID TPDB13985

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 255-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

ATNSSEAFIESIAASAKPVADANGLYPSVMIAQAILESNWGSSQLSRAPYYNLFGIQGTYQGKSVVFKTQEYLNGKWVTKDMPFRVYPSFNQSFQDNTYVLKTTNFGNGPYYAKAWRANAATYQDATAALTGKYATDPSYGASLNRIISQYNLTRFDGASSAGNTNSGGSTTTNTNNNSGTNSSSTTYTVKSGDTLWGISQRYGISVAQIQSANNLKSTIIYIGQKLLLTGSASSTNSGGSNNSASTTPTTSVTP

FASTA

>TPDB13985|Antibacterial|length=255
ATNSSEAFIESIAASAKPVADANGLYPSVMIAQAILESNWGSSQLSRAPYYNLFGIQGTYQGKSVVFKTQEYLNGKWVTKDMPFRVYPSFNQSFQDNTYVLKTTNFGNGPYYAKAWRANAATYQDATAALTGKYATDPSYGASLNRIISQYNLTRFDGASSAGNTNSGGSTTTNTNNNSGTNSSSTTYTVKSGDTLWGISQRYGISVAQIQSANNLKSTIIYIGQKLLLTGSASSTNSGGSNNSASTTPTTSVTP

Formula C1188H1827N325O397S2

Absent Amino Acids CH

Common Amino Acids S

Mass 27078.63

PI 9.63

Basic Residues 17

Acidic Residues 11

Hydrophobic Residues 93

Net Charge +6

Boman Index 15.68

Hydrophobicity -0.426

Aliphatic Index 62.86

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 45840

Absorbance 280nm 169.28

Polar Residues 119

number

26

A

6

R

24

N

7

D

0

C

4

E

13

Q

22

G

0

H

13

I

14

L

11

K

2

M

8

F

9

P

36

S

30

T

4

W

16

Y

10

V

Amino Acid Distribution

A: 26 R: 6 N: 24 D: 7 C: 0 E: 4 Q: 13 G: 22 H: 0 I: 13 L: 14 K: 11 M: 2 F: 8 P: 9 S: 36 T: 30 W: 4 Y: 16 V: 10

Length

255

Formula

C1188H1827N325O397S2

Mass

27078.63

PI

9.63

Net Charge

+6

Boman Index

15.68

Hydrophobicity

-0.426

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.