Back to search

Peptide record

TPDB13966

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
57 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13966
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
dbAMP Peptipedia ACP740 _ACP240 AFP-GFuse Antifungipept CAFPdb dbAMP 3.0 i2APP AVPpred-BWR
standard
No
A 57-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from dbAMP, Peptipedia, ACP740 _ACP240, and other sources, with an available 3D structural model.
Sequence
AQEPVKGPVSTKPGSCPIILIRCAMLNPPNRCLKDTDCPGIKKCCEGSCGMACFVPQ
Physicochemical Analysis
C254H424N72O75S10
HWY
CP
6007.20
8.10
7
4
16
+3
12.66
-0.019
68.42
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
500
8.32
17
Residue Composition
number
3
A
2
R
2
N
2
D
8
C
2
E
2
Q
5
G
0
H
4
I
3
L
5
K
2
M
1
F
8
P
3
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 3 R: 2 N: 2 D: 2 C: 8 E: 2 Q: 2 G: 5 H: 0 I: 4 L: 3 K: 5 M: 2 F: 1 P: 8 S: 3 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
57
C254H424N72O75S10
6007.20
8.10
+3
12.66
-0.019
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
active against P. aeruginosa PAO1 and S. aureus C1705. Virus: Active against HIV-1 and HSV-2 ( Drannik AG, et al 2013 ). The anti-HIV activity of Elafin is 130 times more potent than its precursor serine antiprotease trappin-2 ( Drannik AG, et al 2012 ). Parasites: It is also antiparasitic and malaria ( Roussilhon et al., 2017 ). It also specifically inhibits elastase (see this ref).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
active against P. aeruginosa PAO1 and S. aureus C1705. Virus: Active against HIV-1 and HSV-2 ( Drannik AG, et al 2013 ). The anti-HIV activity of Elafin is 130 times more potent than its precursor serine antiprotease trappin-2 ( Drannik AG, et al 2012 ). Parasites: It is also antiparasitic and malaria ( Roussilhon et al., 2017 ). It also specifically inhibits elastase (see this ref).
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
active against P. aeruginosa PAO1 and S. aureus C1705. Virus: Active against HIV-1 and HSV-2 ( Drannik AG, et al 2013 ). The anti-HIV activity of Elafin is 130 times more potent than its precursor serine antiprotease trappin-2 ( Drannik AG, et al 2012 ). Parasites: It is also antiparasitic and malaria ( Roussilhon et al., 2017 ). It also specifically inhibits elastase (see this ref).
Evidence 4 Activity

Activity

Antiviral

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
active against P. aeruginosa PAO1 and S. aureus C1705. Virus: Active against HIV-1 and HSV-2 ( Drannik AG, et al 2013 ). The anti-HIV activity of Elafin is 130 times more potent than its precursor serine antiprotease trappin-2 ( Drannik AG, et al 2012 ). Parasites: It is also antiparasitic and malaria ( Roussilhon et al., 2017 ). It also specifically inhibits elastase (see this ref).