TPDB

3D PDB MODEL

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TPDB ID TPDB13905

Activity

Antibacterial Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP CAFPdb

Sequence_Type

standard

Has_Modification No

Description A 249-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from dbAMP and CAFPdb, with an available 3D structural model.

Sequence

ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI

FASTA

>TPDB13905|Antibacterial;Antifungal|length=249
ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI

Formula C1178H1768N324O341S3

Absent Amino Acids

Common Amino Acids P

Mass 26021.14

PI 8.92

Basic Residues 22

Acidic Residues 15

Hydrophobic Residues 93

Net Charge +2

Boman Index 31.57

Hydrophobicity -0.404

Aliphatic Index 66.31

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 35870

Absorbance 280nm 137.85

Polar Residues 62

number

27

A

9

R

18

N

9

D

1

C

6

E

9

Q

34

G

5

H

10

I

15

L

8

K

2

M

9

F

36

P

14

S

7

T

3

W

13

Y

14

V

Amino Acid Distribution

A: 27 R: 9 N: 18 D: 9 C: 1 E: 6 Q: 9 G: 34 H: 5 I: 10 L: 15 K: 8 M: 2 F: 9 P: 36 S: 14 T: 7 W: 3 Y: 13 V: 14

Length

249

Formula

C1178H1768N324O341S3

Mass

26021.14

PI

8.92

Net Charge

+2

Boman Index

31.57

Hydrophobicity

-0.404

Evidence 1 Activity

Source & Reference

Database Source dbAMP CAFPdb