TPDB

3D PDB MODEL

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TPDB ID TPDB13876

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

dbAMP

Sequence_Type

standard

Has_Modification No

Description A 169-aa standard natural antibacterial peptide sequence curated from dbAMP, with an available 3D structural model.

Sequence

AAFFAQQKGLPTQQQNQVSPKAVSMIVNLEGCVRNPYKCPADVWTNGVGNTHNVDKTKILTIDEVATDLRRNIKEAENCINTYFNGEKMNQGQYDAMVSLAFNVGCGNIKTYYSKTQGKRVATTIYRAAQAENWILMCNRIEDFNKSGGRVLKGLQNRRAKEKALCLGE

FASTA

>TPDB13876|Antibacterial|length=169
AAFFAQQKGLPTQQQNQVSPKAVSMIVNLEGCVRNPYKCPADVWTNGVGNTHNVDKTKILTIDEVATDLRRNIKEAENCINTYFNGEKMNQGQYDAMVSLAFNVGCGNIKTYYSKTQGKRVATTIYRAAQAENWILMCNRIEDFNKSGGRVLKGLQNRRAKEKALCLGE

Formula C819H1314N242O250S10

Absent Amino Acids

Common Amino Acids N

Mass 18871.51

PI 9.41

Basic Residues 24

Acidic Residues 15

Hydrophobic Residues 63

Net Charge +8

Boman Index 37.86

Hydrophobicity -0.528

Aliphatic Index 73.31

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 20315

Absorbance 280nm 107.65

Polar Residues 56

number

15

A

9

R

17

N

6

D

6

C

9

E

11

Q

13

G

1

H

9

I

10

L

14

K

4

M

5

F

4

P

5

S

11

T

2

W

6

Y

12

V

Amino Acid Distribution

A: 15 R: 9 N: 17 D: 6 C: 6 E: 9 Q: 11 G: 13 H: 1 I: 9 L: 10 K: 14 M: 4 F: 5 P: 4 S: 5 T: 11 W: 2 Y: 6 V: 12

Length

169

Formula

C819H1314N242O250S10

Mass

18871.51

PI

9.41

Net Charge

+8

Boman Index

37.86

Hydrophobicity

-0.528

Evidence 1 Activity

Source & Reference

Database Source dbAMP

Other

Source Activity Label	Source Definition
Antibacterial	dbAMP classified as Antibacterial under the Anti-bacterial function class.