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Peptide record

TPDB13860

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13860
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept APD_complete APD_hemolytic Hemolytic2 ToxinPred 3.0
standard
No
A 19-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FIGAILPAIAGLVHGLINR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C92H153N25O21
DCEQKMSTWY
I
1945.38
11.05
2
0
12
+1
-1.24
1.463
174.74
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
3
A
1
R
1
N
0
D
0
C
0
E
0
Q
3
G
1
H
4
I
3
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 4 L: 3 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
19 reviewed residue count
C92H153N25O21 sequence-only estimate (linear, free termini)
1945.38 sequence-only estimate (linear, free termini)
11.05 sequence-only estimate (linear, free termini)
+1 sequence-only estimate (linear, free termini)
-1.24 sequence-only estimate (linear, free termini)
1.463 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Hemolysis
[Ref.15638808]Show hemolytic activity against human red blood cells

Target

human red blood cells

Source & Reference

APD_complete APD_hemolytic
DRAMP4
Protein Pept Lett. 2005 Jan 12(1):89-93.

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.
Evidence 2 Activity

Activity

Toxicity
Hemolytic
Hemolytic_activity: [Ref.15638808]Show hemolytic activity against human red blood cells

Target

erythrocytes

Source & Reference

NA
DRAMP
Protein Pept Lett. 2005 Jan 12(1):89-93.
Evidence 3 Hemolysis

Activity

[Ref.15638808]Show hemolytic activity against human red blood cells
Hemolysis

Target

human red blood cells

Source & Reference

APD_complete APD_hemolytic
Protein Pept Lett. 2005 Jan 12(1):89-93.
DRAMP4
APD_complete APD_hemolytic