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Peptide record

TPDB13859

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB13859
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 33-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GLWSTIKQKGKEAAIAAAKAAGKAVLNAASEAL
Physicochemical Analysis
C144H245N41O43
RDCHMFPY
A
3238.78
10.38
5
2
18
+3
4.47
0.197
101.21
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
169.82
5
Residue Composition
number
11
A
0
R
1
N
0
D
0
C
2
E
1
Q
3
G
0
H
2
I
3
L
5
K
0
M
0
F
0
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 11 R: 0 N: 1 D: 0 C: 0 E: 2 Q: 1 G: 3 H: 0 I: 2 L: 3 K: 5 M: 0 F: 0 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
33
C144H245N41O43
3238.78
10.38
+3
4.47
0.197
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>10 µM
Cytotoxic
50% Cytotoxicity | >10 | µM | target cell: Murine peritoneal macrophages

Target

Murine peritoneal macrophages

Source & Reference

NA
DBAASP
Antimicrobial peptides isolated from Phyllomedusa nordestina (Amphibia) alter the permeability of plasma membrane of Leishmania and Trypanosoma cruzi. | Exp Parasitol | 2013