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Peptide record

TPDB13857

Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB13857
Antibacterial Anticancer Antifungal Antiparasitic Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia AntiCP 2.0 iACP-DRLF Antifp Antifungipept i2APP dbAMP 3.0 ToxinPred 3.0
standard
No
A 19-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
FLSLIPTAINAVSALAKHF
Physicochemical Analysis
C96H153N23O24
RDCEQGMWY
A
2013.41
10.10
2
0
12
+1
-1.95
1.205
138.95
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
2
I
3
L
1
K
0
M
2
F
1
P
2
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 2 L: 3 K: 1 M: 0 F: 2 P: 1 S: 2 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
19
C96H153N23O24
2013.41
10.10
+1
-1.95
1.205
Evidence Records 5 records
Evidence 1 Activity

Activity

IC50
Antibacterial
0.46 µM

Target

T. cruzi

Source & Reference

NA

Other

Parasites: inhibited T. cruzi (IC50 0.46 uM).
Evidence 2 Activity

Activity

IC50
Antifungal
0.46 µM

Target

T. cruzi

Source & Reference

Antifungipept

Other

Parasites: inhibited T. cruzi (IC50 0.46 uM).
Evidence 3 Activity

Activity

IC50
Antiparasitic
0.46 µM

Target

T. cruzi

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiparasitic
dbAMP 3.0 classified under the Anti-parasitic function class.
Parasites: inhibited T. cruzi (IC50 0.46 uM).
Evidence 4 Activity

Activity

IC50
Antiviral
0.46 µM

Target

T. cruzi

Source & Reference

dbAMP 3.0

Other

Source Activity Label Source Definition
Antiviral
dbAMP 3.0 classified under the Anti-viral function class.
Parasites: inhibited T. cruzi (IC50 0.46 uM).
Evidence 5 Activity

Activity

50% Cytotoxicity
Toxicity
>10 µM
Cytotoxic
50% Cytotoxicity | >10 | µM | target cell: Murine peritoneal macrophages

Target

Murine peritoneal macrophages

Source & Reference

NA
DBAASP
Antimicrobial peptides isolated from Phyllomedusa nordestina (Amphibia) alter the permeability of plasma membrane of Leishmania and Trypanosoma cruzi. | Exp Parasitol | 2013