Peptide record

TPDB13846

Antibacterial Toxicity standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB13846
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 49-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
PIMYKVPLIRKKSLRRTLSERGLLKDPFLKKHNLNPARKYFPQWKAPTL
Physicochemical Analysis
C275H450N78O63S1
C
LK
5889.14
11.59
14
2
19
+11
9.26
-0.739
89.59
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
8480
143.99
9
Residue Composition
number
2
A
5
R
2
N
1
D
0
C
1
E
1
Q
1
G
1
H
2
I
8
L
8
K
1
M
2
F
6
P
2
S
2
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 5 N: 2 D: 1 C: 0 E: 1 Q: 1 G: 1 H: 1 I: 2 L: 8 K: 8 M: 1 F: 2 P: 6 S: 2 T: 2 W: 1 Y: 2 V: 1
Chemical Descriptors
49
C275H450N78O63S1
5889.14
11.59
+11
9.26
-0.739
Evidence Records 2 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
40 µM
Hemolytic Cytotoxic
0% Hemolysis | 40 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. | ACS Synth Biol | 2018
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. | ACS Synth Biol | 2018