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Peptide record

TPDB13845

Antibacterial Anticancer Antifungal Antiparasitic standard
48 amino acids
Basic Information
3D PDB MODEL
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TPDB13845
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF
standard
No
A 48-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
MSKRDCNLMKACCAGQAVTYAIHSLLNRLGGDSSDPAGCNDIVRKYCK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C214H355N67O68S7
EFW
AC
5179.00
8.46
8
4
17
+3
1.81
-0.252
71.25
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3230
0.62
16
Residue Composition
number
5
A
3
R
3
N
4
D
5
C
0
E
1
Q
4
G
1
H
2
I
4
L
4
K
2
M
0
F
1
P
4
S
1
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 5 R: 3 N: 3 D: 4 C: 5 E: 0 Q: 1 G: 4 H: 1 I: 2 L: 4 K: 4 M: 2 F: 0 P: 1 S: 4 T: 1 W: 0 Y: 2 V: 2
Chemical Descriptors
48 reviewed residue count
C214H355N67O68S7 sequence-only estimate (linear, free termini)
5179.00 sequence-only estimate (linear, free termini)
8.46 sequence-only estimate (linear, free termini)
+3 sequence-only estimate (linear, free termini)
1.81 sequence-only estimate (linear, free termini)
-0.252 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active mainly against tested Gram+ bacteria E. faecalis, E. faecium, E. hirae, E. pseudoavium, E. sulfureus, E. saccharolyticus, E. columbae, L. plantarum, L. paracasei, L. lactis, L. mesenteroides, B. subtilis, B. cereus, L. innocua, L. monocytogenes, S. xylosus, S. aureus, and some sensitive Gram-S. enterica serovar Typhimurium.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active mainly against tested Gram+ bacteria E. faecalis, E. faecium, E. hirae, E. pseudoavium, E. sulfureus, E. saccharolyticus, E. columbae, L. plantarum, L. paracasei, L. lactis, L. mesenteroides, B. subtilis, B. cereus, L. innocua, L. monocytogenes, S. xylosus, S. aureus, and some sensitive Gram-S. enterica serovar Typhimurium.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active mainly against tested Gram+ bacteria E. faecalis, E. faecium, E. hirae, E. pseudoavium, E. sulfureus, E. saccharolyticus, E. columbae, L. plantarum, L. paracasei, L. lactis, L. mesenteroides, B. subtilis, B. cereus, L. innocua, L. monocytogenes, S. xylosus, S. aureus, and some sensitive Gram-S. enterica serovar Typhimurium.