Peptide record

TPDB13844

Antibacterial Antifungal standard
47 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13844
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 47-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
RTCESQSHKFKGPCASDHNCASVCQTERFSGGRCRGFRRRCFCTTHC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C215H339N79O66S8
ILMWY
C
5343.03
8.77
12
3
7
+6
3.47
-0.870
10.43
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
500
0.09
20
Residue Composition
number
2
A
7
R
1
N
1
D
8
C
2
E
2
Q
4
G
3
H
0
I
0
L
2
K
0
M
4
F
1
P
5
S
4
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 7 N: 1 D: 1 C: 8 E: 2 Q: 2 G: 4 H: 3 I: 0 L: 0 K: 2 M: 0 F: 4 P: 1 S: 5 T: 4 W: 0 Y: 0 V: 1
Chemical Descriptors
47 reviewed residue count
C215H339N79O66S8 sequence-only estimate (linear, free termini)
5343.03 sequence-only estimate (linear, free termini)
8.77 sequence-only estimate (linear, free termini)
+6 sequence-only estimate (linear, free termini)
3.47 sequence-only estimate (linear, free termini)
-0.870 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against fungus F. graminearum that causes head blight disease in cereals.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against fungus F. graminearum that causes head blight disease in cereals.