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Peptide record

TPDB13834

Antibacterial Toxicity standard
46 amino acids
Basic Information
3D PDB MODEL
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TPDB13834
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 46-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
MGIINTLQKYYCRVRGGRCAVLSCLPKEEQIGKCSTRGRKCCRRKK
Physicochemical Analysis
C221H386N76O60S7
DHFW
R
5292.39
10.43
13
2
12
+11
12.08
-0.643
65.65
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
3355
63.39
15
Residue Composition
number
1
A
7
R
1
N
0
D
6
C
2
E
2
Q
5
G
0
H
3
I
3
L
6
K
1
M
0
F
1
P
2
S
2
T
0
W
2
Y
2
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 6 E: 2 Q: 2 G: 5 H: 0 I: 3 L: 3 K: 6 M: 1 F: 0 P: 1 S: 2 T: 2 W: 0 Y: 2 V: 2
Chemical Descriptors
46
C221H386N76O60S7
5292.39
10.43
+11
12.08
-0.643
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Bacterial expression and antibiotic activities of recombinant variants of human ?-defensins on pathogenic bacteria and M. tuberculosis. | Protein Expr Purif | 2013