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Peptide record

TPDB13830

Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
45 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13830
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 45-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
RTCMKKEGWGKCLIDTTCAHSCKNRGYIGGNCKGMTRTCYCLVNC
Physicochemical Analysis
C205H337N65O61S10
QFP
C
5008.93
8.73
9
2
11
+6
5.79
-0.389
43.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
8980
179.28
19
Residue Composition
number
1
A
3
R
3
N
1
D
8
C
1
E
0
Q
6
G
1
H
2
I
2
L
5
K
2
M
0
F
0
P
1
S
5
T
1
W
2
Y
1
V
Amino Acid Distribution
A: 1 R: 3 N: 3 D: 1 C: 8 E: 1 Q: 0 G: 6 H: 1 I: 2 L: 2 K: 5 M: 2 F: 0 P: 0 S: 1 T: 5 W: 1 Y: 2 V: 1
Chemical Descriptors
45
C205H337N65O61S10
5008.93
8.73
+6
5.79
-0.389
Evidence Records 40 records
Evidence 1 Activity

Activity

IC50
Antibacterial
30-53.2 µg/mL

Target

p. pisi

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
VaD1 inhibited the growth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicat
Evidence 2 Activity

Activity

IC50
Antibacterial
36.6 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP

Other

owth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cer
Evidence 3 Activity

Activity

IC50
Antibacterial
40.8 µg/mL

Target

v. vesicatoria

Source & Reference

dbAMP DRAMP

Other

3.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml),
Evidence 4 Activity

Activity

IC50
Antibacterial
143.4 µg/mL

Target

S.typhimurium

Source & Reference

dbAMP DRAMP

Other

g/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50
Evidence 5 Activity

Activity

IC50
Antibacterial
>500 µg/mL

Target

B.cereus

Source & Reference

dbAMP DRAMP

Other

g/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC5
Evidence 6 Activity

Activity

IC50
Antibacterial
>500 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP

Other

icatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteriti
Evidence 7 Activity

Activity

IC50
Antibacterial
1000 µg/mL

Target

v. carotovora

Source & Reference

dbAMP DRAMP

Other

m (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syri
Evidence 8 Activity

Activity

IC50
Antibacterial
>1000 µg/mL

Target

P.vulgaris

Source & Reference

dbAMP DRAMP

Other

C50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 a
Evidence 9 Activity

Activity

IC50
Antibacterial
>1000 µg/mL

Target

S.enteritidis

Source & Reference

dbAMP DRAMP

Other

500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein syn
Evidence 10 Activity

Activity

IC50
Antibacterial
>1000 µg/mL

Target

v. syringae

Source & Reference

dbAMP DRAMP

Other

ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein synthesis and bruchid larval development. Updated 7
Evidence 11 Activity

Activity

IC50
Antifungal
30-53.2 µg/mL

Target

p. pisi

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
VaD1 inhibited the growth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicat
Evidence 12 Activity

Activity

IC50
Antifungal
36.6 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

owth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cer
Evidence 13 Activity

Activity

IC50
Antifungal
40.8 µg/mL

Target

v. vesicatoria

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

3.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml),
Evidence 14 Activity

Activity

IC50
Antifungal
143.4 µg/mL

Target

S.typhimurium

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50
Evidence 15 Activity

Activity

IC50
Antifungal
>500 µg/mL

Target

B.cereus

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

g/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC5
Evidence 16 Activity

Activity

IC50
Antifungal
>500 µg/mL

Target

E.coli

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

icatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteriti
Evidence 17 Activity

Activity

IC50
Antifungal
1000 µg/mL

Target

v. carotovora

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

m (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syri
Evidence 18 Activity

Activity

IC50
Antifungal
>1000 µg/mL

Target

P.vulgaris

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

C50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 a
Evidence 19 Activity

Activity

IC50
Antifungal
>1000 µg/mL

Target

S.enteritidis

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein syn
Evidence 20 Activity

Activity

IC50
Antifungal
>1000 µg/mL

Target

v. syringae

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein synthesis and bruchid larval development. Updated 7
Evidence 21 Activity

Activity

IC50
Antiparasitic
30-53.2 µg/mL

Target

p. pisi

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
VaD1 inhibited the growth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicat
Evidence 22 Activity

Activity

IC50
Antiparasitic
36.6 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

owth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cer
Evidence 23 Activity

Activity

IC50
Antiparasitic
40.8 µg/mL

Target

v. vesicatoria

Source & Reference

DRAMP

Other

3.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml),
Evidence 24 Activity

Activity

IC50
Antiparasitic
143.4 µg/mL

Target

S.typhimurium

Source & Reference

DRAMP

Other

g/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50
Evidence 25 Activity

Activity

IC50
Antiparasitic
>500 µg/mL

Target

B.cereus

Source & Reference

DRAMP

Other

g/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC5
Evidence 26 Activity

Activity

IC50
Antiparasitic
>500 µg/mL

Target

E.coli

Source & Reference

DRAMP

Other

icatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteriti
Evidence 27 Activity

Activity

IC50
Antiparasitic
1000 µg/mL

Target

v. carotovora

Source & Reference

DRAMP

Other

m (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syri
Evidence 28 Activity

Activity

IC50
Antiparasitic
>1000 µg/mL

Target

P.vulgaris

Source & Reference

DRAMP

Other

C50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 a
Evidence 29 Activity

Activity

IC50
Antiparasitic
>1000 µg/mL

Target

S.enteritidis

Source & Reference

DRAMP

Other

500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein syn
Evidence 30 Activity

Activity

IC50
Antiparasitic
>1000 µg/mL

Target

v. syringae

Source & Reference

DRAMP

Other

ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein synthesis and bruchid larval development. Updated 7
Evidence 31 Activity

Activity

IC50
Antiviral
30-53.2 µg/mL

Target

p. pisi

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiviral
DRAMP antiviral activity supported by activity records against viral targets.
VaD1 inhibited the growth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicat
Evidence 32 Activity

Activity

IC50
Antiviral
36.6 µg/mL

Target

Staphylococcus epidermidis

Source & Reference

DRAMP

Other

owth of fungi F. oxysporum f. sp. pisi (IC50 30-53.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cer
Evidence 33 Activity

Activity

IC50
Antiviral
40.8 µg/mL

Target

v. vesicatoria

Source & Reference

DRAMP

Other

3.2 ug/ml), T.rubrum (IC50 > 500 ug/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml),
Evidence 34 Activity

Activity

IC50
Antiviral
143.4 µg/mL

Target

S.typhimurium

Source & Reference

DRAMP

Other

g/ml), S. epidermidis (IC50 36.6 ug/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50
Evidence 35 Activity

Activity

IC50
Antiviral
>500 µg/mL

Target

B.cereus

Source & Reference

DRAMP

Other

g/ml), X. campestris pv. vesicatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC5
Evidence 36 Activity

Activity

IC50
Antiviral
>500 µg/mL

Target

E.coli

Source & Reference

DRAMP

Other

icatoria (IC50 40.8 ug/ml), S.typhimurium (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteriti
Evidence 37 Activity

Activity

IC50
Antiviral
1000 µg/mL

Target

v. carotovora

Source & Reference

DRAMP

Other

m (IC50 143.4 ug/ml), B.cereus (IC50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syri
Evidence 38 Activity

Activity

IC50
Antiviral
>1000 µg/mL

Target

P.vulgaris

Source & Reference

DRAMP

Other

C50 >500 ug/ml), E.coli (IC50 >500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 a
Evidence 39 Activity

Activity

IC50
Antiviral
>1000 µg/mL

Target

S.enteritidis

Source & Reference

DRAMP

Other

500 ug/ml), E.carotovora pv. carotovora (IC50 1000 ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein syn
Evidence 40 Activity

Activity

IC50
Antiviral
>1000 µg/mL

Target

v. syringae

Source & Reference

DRAMP

Other

ug/ml), P.vulgaris (IC50 >1000 ug/ml), S.enteritidis (IC50 >1000 ug/ml), and P.syringae pv. syringae (IC50 >1000 ug/ml). VaD1 also inhibited in vitro protein synthesis and bruchid larval development. Updated 7