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Peptide record

TPDB13810

Antibacterial Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB13810
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 42-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GFGCPGSEKKCHNHCKTIKGYKGGYCDGPYIPFVGRPRCKCY
Physicochemical Analysis
C205H309N59O54S6
AQLMW
G
4656.43
9.11
10
2
9
+6
7.29
-0.757
25.48
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
6335
136.05
13
Residue Composition
number
0
A
2
R
1
N
1
D
6
C
1
E
0
Q
8
G
2
H
2
I
0
L
6
K
0
M
2
F
4
P
1
S
1
T
0
W
4
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 1 C: 6 E: 1 Q: 0 G: 8 H: 2 I: 2 L: 0 K: 6 M: 0 F: 2 P: 4 S: 1 T: 1 W: 0 Y: 4 V: 1
Chemical Descriptors
42
C205H309N59O54S6
4656.43
9.11
+6
7.29
-0.757
Evidence Records 2 records
Evidence 1 Activity

Activity

15% Killing
Toxicity
50 µM
Cytotoxic
15% Killing | 50 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Invasive fungi-derived defensins kill drug-resistant bacterial pathogens. | Peptides | 2018
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
10% Hemolysis | 50 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Invasive fungi-derived defensins kill drug-resistant bacterial pathogens. | Peptides | 2018