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Peptide record

TPDB13808

Antibacterial Antifungal Toxicity standard
42 amino acids
Basic Information
3D PDB MODEL
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TPDB13808
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 42-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
APKVNVNALKKGGRVIKKGLGVIGAAGTAHEVYNHVRNRNQG
Physicochemical Analysis
C191H324N66O53
DCMFSW
G
4393.08
11.60
10
1
16
+7
11.55
-0.464
90.48
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
33.92
8
Residue Composition
number
5
A
3
R
5
N
0
D
0
C
1
E
1
Q
7
G
2
H
2
I
2
L
5
K
0
M
0
F
1
P
0
S
1
T
0
W
1
Y
6
V
Amino Acid Distribution
A: 5 R: 3 N: 5 D: 0 C: 0 E: 1 Q: 1 G: 7 H: 2 I: 2 L: 2 K: 5 M: 0 F: 0 P: 1 S: 0 T: 1 W: 0 Y: 1 V: 6
Chemical Descriptors
42
C191H324N66O53
4393.08
11.60
+7
11.55
-0.464
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Recombinant: Active against Gram+ (S. aureus, B. cereus, and B. subtilis, MIC 2.8-6.3 uM), Gram- (E. coli DH5alpha, E. coli K12D31, P. fluorescent, S. choleraesuis, MIC 1.1-5 uM), and fungi (A. pullulans, MIC 3.5 uM A. flavus, B. cinerea, P. litchi, A. fumigatus, F. oxysporum, MIC 8.9-23 uM).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Recombinant: Active against Gram+ (S. aureus, B. cereus, and B. subtilis, MIC 2.8-6.3 uM), Gram- (E. coli DH5alpha, E. coli K12D31, P. fluorescent, S. choleraesuis, MIC 1.1-5 uM), and fungi (A. pullulans, MIC 3.5 uM A. flavus, B. cinerea, P. litchi, A. fumigatus, F. oxysporum, MIC 8.9-23 uM).
Evidence 3 Activity

Activity

0% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
0% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Molecular Identification of a Moricin Family Antimicrobial Peptide (Px-Mor) From Plutella xylostella With Activities Against the Opportunistic Human Pathogen Aureobasidium pullulans. | Front Microbiol | 2019