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Peptide record

TPDB13801

Antibacterial Anticancer Antifungal Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB13801
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
GFLKKIGKKLEGAVQRTRDATIQTIAVAQAAANVAATAKQ
Physicochemical Analysis
C181H314N56O54
CHMPSWY
A
4138.83
11.08
7
2
19
+5
8.48
-0.062
95.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
9
Residue Composition
number
10
A
2
R
1
N
1
D
0
C
1
E
4
Q
3
G
0
H
3
I
2
L
5
K
0
M
1
F
0
P
0
S
4
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 10 R: 2 N: 1 D: 1 C: 0 E: 1 Q: 4 G: 3 H: 0 I: 3 L: 2 K: 5 M: 0 F: 1 P: 0 S: 0 T: 4 W: 0 Y: 0 V: 3
Chemical Descriptors
40
C181H314N56O54
4138.83
11.08
+5
8.48
-0.062
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4-8 µg/mL

Target

Escherichia coli D31 or ATCC 25922

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Amidated is more active against E. coli D31 or ATCC 25922 (MIC 4-8 µg/mL), K. pneumoniae DSM 30104 (4 µg/mL), A. baumannii ATCC.19606 (MIC 8 µg/mL)
Evidence 2 Activity

Activity

MIC
Antibacterial
8 µg/mL

Target

C.19606

Source & Reference

dbAMP

Other

oli D31 or ATCC 25922 (MIC 4-8 µg/mL), K. pneumoniae DSM 30104 (4 µg/mL), A. baumannii ATCC.19606 (MIC 8 µg/mL)
Evidence 3 Activity

Activity

MIC
Antifungal
4-8 µg/mL

Target

Escherichia coli D31 or ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Amidated is more active against E. coli D31 or ATCC 25922 (MIC 4-8 µg/mL), K. pneumoniae DSM 30104 (4 µg/mL), A. baumannii ATCC.19606 (MIC 8 µg/mL)
Evidence 4 Activity

Activity

MIC
Antifungal
8 µg/mL

Target

C.19606

Source & Reference

dbAMP CAFPdb Antifungipept

Other

oli D31 or ATCC 25922 (MIC 4-8 µg/mL), K. pneumoniae DSM 30104 (4 µg/mL), A. baumannii ATCC.19606 (MIC 8 µg/mL)
Evidence 5 Activity

Activity

Toxicity
Hemolytic Cytotoxic
- | NA | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Peptides from Rat-Tailed Maggots of the Drone Fly Eristalis tenax Show Potent Activity against Multidrug-Resistant Gram-Negative Bacteria. | Microorganisms | 2020
Evidence 6 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: Not active up to 1024 µg/ml | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Microorganisms. 2020 Apr 25 8(5):626