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Peptide record

TPDB13793

Antibacterial Antifungal standard
40 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13793
Antibacterial Antifungal
Anti-infective peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 40-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
RRSIFRKLRRKIKKGLKKGIQHLLAGGRQGLPQGGRPGMI
Physicochemical Analysis
C199H354N72O45S1
NDCETWYV
G
4507.52
13.18
14
0
12
+13
9.85
-0.807
90.25
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
7
R
0
N
0
D
0
C
0
E
3
Q
8
G
1
H
4
I
5
L
6
K
1
M
1
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 8 H: 1 I: 4 L: 5 K: 6 M: 1 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
40
C199H354N72O45S1
4507.52
13.18
+13
9.85
-0.807
Evidence Records 24 records
Evidence 1 Activity

Activity

MIC
Antibacterial
9.3 ug/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram- E. coli ATCC25922 (MIC 9.3 ug/mL), some clinical strains (MIC 4.69 - >200 ug/mL), S. dysenteriae (4.69 ug/ml), K. Pneumonia
Evidence 2 Activity

Activity

MIC
Antibacterial
75->200 µg/mL

Target

K. Pneumoniae

Source & Reference

dbAMP

Other

C 9.3 ug/mL), some clinical strains (MIC 4.69 - >200 ug/mL), S. dysenteriae (4.69 ug/ml), K. Pneumoniae (MIC 75- >200 ug/ml), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S
Evidence 3 Activity

Activity

MIC
Antibacterial
9.38 ug/mL

Target

Stenotrophomonas maltophilia

Source & Reference

dbAMP

Other

(MIC 4.69 - >200 ug/mL), S. dysenteriae (4.69 ug/ml), K. Pneumoniae (MIC 75- >200 ug/ml), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18
Evidence 4 Activity

Activity

MIC
Antibacterial
4.69 µg/mL

Target

Pseudomonas aeruginosa clinical strain

Source & Reference

dbAMP

Other

teriae (4.69 ug/ml), K. Pneumoniae (MIC 75- >200 ug/ml), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subt
Evidence 5 Activity

Activity

MIC
Antibacterial
18.75-75 µg/mL

Target

Staphylococcus aureus clinical strains

Source & Reference

dbAMP

Other

), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC
Evidence 6 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

B. cereus

Source & Reference

dbAMP

Other

clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albi
Evidence 7 Activity

Activity

MIC
Antibacterial
18.75 µg/mL

Target

B. subtilis

Source & Reference

dbAMP

Other

ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aq
Evidence 8 Activity

Activity

MIC
Antibacterial
4.69 µg/mL

Target

N. asteroides

Source & Reference

dbAMP

Other

MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug
Evidence 9 Activity

Activity

MIC
Antibacterial
1.17->200 µg/mL

Target

Candida albicans

Source & Reference

dbAMP

Other

ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii
Evidence 10 Activity

Activity

MIC
Antibacterial
18.7 µg/mL

Target

V. brasiliensis

Source & Reference

dbAMP

Other

asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii (MIC 75 ug/ml), E. tarda (MIC 18.75 ug/ml).
Evidence 11 Activity

Activity

MIC
Antibacterial
75 µg/mL

Target

A. veronii

Source & Reference

dbAMP

Other

200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii (MIC 75 ug/ml), E. tarda (MIC 18.75 ug/ml).
Evidence 12 Activity

Activity

MIC
Antibacterial
18.75 µg/mL

Target

E. tarda

Source & Reference

dbAMP

Other

ns V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii (MIC 75 ug/ml), E. tarda (MIC 18.75 ug/ml).
Evidence 13 Activity

Activity

MIC
Antifungal
9.3 ug/mL

Target

Escherichia coli ATCC25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram- E. coli ATCC25922 (MIC 9.3 ug/mL), some clinical strains (MIC 4.69 - >200 ug/mL), S. dysenteriae (4.69 ug/ml), K. Pneumonia
Evidence 14 Activity

Activity

MIC
Antifungal
75->200 µg/mL

Target

K. Pneumoniae

Source & Reference

dbAMP CAFPdb Antifungipept

Other

C 9.3 ug/mL), some clinical strains (MIC 4.69 - >200 ug/mL), S. dysenteriae (4.69 ug/ml), K. Pneumoniae (MIC 75- >200 ug/ml), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S
Evidence 15 Activity

Activity

MIC
Antifungal
9.38 ug/mL

Target

Stenotrophomonas maltophilia

Source & Reference

dbAMP CAFPdb Antifungipept

Other

(MIC 4.69 - >200 ug/mL), S. dysenteriae (4.69 ug/ml), K. Pneumoniae (MIC 75- >200 ug/ml), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18
Evidence 16 Activity

Activity

MIC
Antifungal
4.69 µg/mL

Target

Pseudomonas aeruginosa clinical strain

Source & Reference

dbAMP CAFPdb Antifungipept

Other

teriae (4.69 ug/ml), K. Pneumoniae (MIC 75- >200 ug/ml), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subt
Evidence 17 Activity

Activity

MIC
Antifungal
18.75-75 µg/mL

Target

Staphylococcus aureus clinical strains

Source & Reference

dbAMP CAFPdb Antifungipept

Other

), S. maltophilia (MIC 9.38 ug/mL), P. aeruginosa clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC
Evidence 18 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

B. cereus

Source & Reference

dbAMP CAFPdb Antifungipept

Other

clinical strain (MIC 4.69 ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albi
Evidence 19 Activity

Activity

MIC
Antifungal
18.75 µg/mL

Target

B. subtilis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), Gram+ S. aureus clinical strains (MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aq
Evidence 20 Activity

Activity

MIC
Antifungal
4.69 µg/mL

Target

N. asteroides

Source & Reference

dbAMP CAFPdb Antifungipept

Other

MIC 18.75-75 ug/ml), B. cereus (MIC 75 ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug
Evidence 21 Activity

Activity

MIC
Antifungal
1.17->200 µg/mL

Target

Candida albicans

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ug/ml), B. subtilis (MIC 18.75 ug/ml), E. faecium, N. asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii
Evidence 22 Activity

Activity

MIC
Antifungal
18.7 µg/mL

Target

V. brasiliensis

Source & Reference

dbAMP CAFPdb Antifungipept

Other

asteroides (MIC 4.69 ug/ml), fungi C. albicans (MIC 1.17- >200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii (MIC 75 ug/ml), E. tarda (MIC 18.75 ug/ml).
Evidence 23 Activity

Activity

MIC
Antifungal
75 µg/mL

Target

A. veronii

Source & Reference

dbAMP CAFPdb Antifungipept

Other

200 ug/ml), aquatic pathogens V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii (MIC 75 ug/ml), E. tarda (MIC 18.75 ug/ml).
Evidence 24 Activity

Activity

MIC
Antifungal
18.75 µg/mL

Target

E. tarda

Source & Reference

dbAMP CAFPdb Antifungipept

Other

ns V. brasiliensis (MIC 18.7 ug/ml), V. cholerae (37.5 ug/ml), A. veronii (MIC 75 ug/ml), E. tarda (MIC 18.75 ug/ml).