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Peptide record

TPDB13790

Antibacterial Anticancer Toxicity standard
40 amino acids
Basic Information
3D PDB MODEL
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TPDB13790
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 40-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
ATCDLLSPFKVGHAACALHCIAMGRRGGWCDGRAVCNCRR
Physicochemical Analysis
C177H288N62O48S7
EQY
AC
4277.04
8.60
8
2
15
+4
3.09
0.138
68.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
5875
137.36
9
Residue Composition
number
6
A
5
R
1
N
2
D
6
C
0
E
0
Q
5
G
2
H
1
I
3
L
1
K
1
M
1
F
1
P
1
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 6 R: 5 N: 1 D: 2 C: 6 E: 0 Q: 0 G: 5 H: 2 I: 1 L: 3 K: 1 M: 1 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
40
C177H288N62O48S7
4277.04
8.60
+4
3.09
0.138
Evidence Records 3 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.typhimurium ATCC14028

Source & Reference

NA

Other

CVCC1515 (MIC >128 ug/ml ~30 uM), E.coli CICC21530 (serotype O157:H7) (MIC> 128 ug/ml), S.typhimurium ATCC14028 (MIC >128 ug/ml), S.enteritidis CMCC50336 (MIC >128 ug/ml).
Evidence 2 Activity

Activity

MIC
Antibacterial
>128 µg/mL

Target

S.enteritidis CMCC50336

Source & Reference

NA

Other

CICC21530 (serotype O157:H7) (MIC> 128 ug/ml), S.typhimurium ATCC14028 (MIC >128 ug/ml), S.enteritidis CMCC50336 (MIC >128 ug/ml).
Evidence 3 Activity

Activity

2.31% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
2.31% Hemolysis | 512 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antibacterial and immunomodulatory activities of insect defensins-DLP2 and DLP4 against multidrug-resistant Staphylococcus aureus. | Sci Rep | 2017