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Peptide record

TPDB13784

Antibacterial Anticancer Antifungal Antiparasitic standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB13784
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 39-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GWLKKIGKKIERVGQNTRDATVKGLEVAQQAANVAATVR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C183H315N59O54
CHMFPSY
A
4205.88
11.06
8
3
16
+5
1.94
-0.441
92.56
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
1.31
8
Residue Composition
number
6
A
3
R
2
N
1
D
0
C
2
E
3
Q
4
G
0
H
2
I
2
L
5
K
0
M
0
F
0
P
0
S
3
T
1
W
0
Y
5
V
Amino Acid Distribution
A: 6 R: 3 N: 2 D: 1 C: 0 E: 2 Q: 3 G: 4 H: 0 I: 2 L: 2 K: 5 M: 0 F: 0 P: 0 S: 0 T: 3 W: 1 Y: 0 V: 5
Chemical Descriptors
39 reviewed residue count
C183H315N59O54 sequence-only estimate (linear, free termini)
4205.88 sequence-only estimate (linear, free termini)
11.06 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
1.94 sequence-only estimate (linear, free termini)
-0.441 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against E. coli D31. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against E. coli D31. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Active against E. coli D31. Updated 7/2021