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Peptide record

TPDB13775

Antibacterial Anticancer Antifungal Antiparasitic standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB13775
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept
standard
No
A 38-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KWKIFKKIEHMGQNIRDGLIKAGPAVQVVGQAATIYKG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C192H314N54O49S1
CS
K
4195.00
10.59
8
2
17
+5
0.87
-0.205
95.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
1.67
6
Residue Composition
number
4
A
1
R
1
N
1
D
0
C
1
E
3
Q
5
G
1
H
5
I
1
L
6
K
1
M
1
F
1
P
0
S
1
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 4 R: 1 N: 1 D: 1 C: 0 E: 1 Q: 3 G: 5 H: 1 I: 5 L: 1 K: 6 M: 1 F: 1 P: 1 S: 0 T: 1 W: 1 Y: 1 V: 3
Chemical Descriptors
38 reviewed residue count
C192H314N54O49S1 sequence-only estimate (linear, free termini)
4195.00 sequence-only estimate (linear, free termini)
10.59 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
0.87 sequence-only estimate (linear, free termini)
-0.205 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
inhibition zone assay: More active against G- than G+ bacteria: Gram- (22.2-36.3 mm2): E. coli K12 or D21, E. cloacae KCTC2361, Gram+ (0.8-7.1 mm2): B. megaterium Bm11, M. luteus KCTC1056. Fungi A. niger and C. albicans.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
inhibition zone assay: More active against G- than G+ bacteria: Gram- (22.2-36.3 mm2): E. coli K12 or D21, E. cloacae KCTC2361, Gram+ (0.8-7.1 mm2): B. megaterium Bm11, M. luteus KCTC1056. Fungi A. niger and C. albicans.
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

inhibition zone assay: More active against G- than G+ bacteria: Gram- (22.2-36.3 mm2): E. coli K12 or D21, E. cloacae KCTC2361, Gram+ (0.8-7.1 mm2): B. megaterium Bm11, M. luteus KCTC1056. Fungi A. niger and C. albicans.