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Peptide record

TPDB13764

Antibacterial Antifungal Toxicity standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB13764
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept CAFPdb
standard
No
A 38-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
MAGGKAGKDSGKAKAKAVSRSARAGLQFPVGRIHRHLK
Physicochemical Analysis
C170H293N61O45S1
NCETWY
A
3943.64
12.43
12
1
14
+9
9.97
-0.616
64.47
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
4
Residue Composition
number
7
A
4
R
0
N
1
D
0
C
0
E
1
Q
6
G
2
H
1
I
2
L
6
K
1
M
1
F
1
P
3
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 7 R: 4 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 6 H: 2 I: 1 L: 2 K: 6 M: 1 F: 1 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
38
C170H293N61O45S1
3943.64
12.43
+9
9.97
-0.616
Evidence Records 4 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against G+ bacteria (S. aureus, C. glutamicum, B. subtilis, M. lysodeikticus, M. luteus) and G- bacteria (S. flexneri, P. stutzeri, and P. fluorescens) (MIC < 1.5 uM). Updated 8/2019
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against G+ bacteria (S. aureus, C. glutamicum, B. subtilis, M. lysodeikticus, M. luteus) and G- bacteria (S. flexneri, P. stutzeri, and P. fluorescens) (MIC < 1.5 uM). Updated 8/2019
Evidence 3 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Mouse osteoblastic cells MC3T3-E1

Target

Mouse osteoblastic cells MC3T3-E1

Source & Reference

NA
DBAASP
Mechanism study on a new antimicrobial peptide Sphistin derived from the N-terminus of crab histone H2A identified in haemolymphs of Scylla paramamosain. | Fish Shellfish Immunol | 2015
Evidence 4 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Crab haemocytes

Target

Crab haemocytes

Source & Reference

NA
DBAASP
Mechanism study on a new antimicrobial peptide Sphistin derived from the N-terminus of crab histone H2A identified in haemolymphs of Scylla paramamosain. | Fish Shellfish Immunol | 2015