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Peptide record

TPDB13756

Antibacterial Anticancer Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB13756
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
RWKLFKKIEKVGRNVRDGLIKAGPAIAVIGQAKSLGK
Physicochemical Analysis
C185H318N56O45
CHMTY
K
4046.91
11.66
10
2
16
+8
7.87
-0.219
108.11
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
135.91
3
Residue Composition
number
4
A
3
R
1
N
1
D
0
C
1
E
1
Q
5
G
0
H
4
I
3
L
7
K
0
M
1
F
1
P
1
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 1 G: 5 H: 0 I: 4 L: 3 K: 7 M: 0 F: 1 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
37
C185H318N56O45
4046.91
11.66
+8
7.87
-0.219
Evidence Records 2 records
Evidence 1 Activity

Activity

40% Killing
Toxicity
100 µg/mL
Cytotoxic
40% Killing | 100 | µg/mL | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Antibacterial Activity of Rationally Designed Antimicrobial Peptides. | Int J Microbiol | 2020
Evidence 2 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: HEK293T: 40% Killing=100µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Int J Microbiol. 2020 Apr 8 2020:2131535.