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Peptide record

TPDB13751

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB13751
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept APD_complete APD_hemolytic Hemolytic2
standard
No
A 37-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
WNPFKELERAGQRVRDAIISAAPAVATVGQAAAIARG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C170H278N54O49
CHMY
A
3862.41
11.15
5
3
19
+2
1.44
0.027
92.70
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
1.42
5
Residue Composition
number
10
A
4
R
1
N
1
D
0
C
2
E
2
Q
3
G
0
H
3
I
1
L
1
K
0
M
1
F
2
P
1
S
1
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 10 R: 4 N: 1 D: 1 C: 0 E: 2 Q: 2 G: 3 H: 0 I: 3 L: 1 K: 1 M: 0 F: 1 P: 2 S: 1 T: 1 W: 1 Y: 0 V: 3
Chemical Descriptors
37 reviewed residue count
C170H278N54O49 sequence-only estimate (linear, free termini)
3862.41 sequence-only estimate (linear, free termini)
11.15 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
1.44 sequence-only estimate (linear, free termini)
0.027 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP APD_complete APD_hemolytic Antifungipept
Evidence 2 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.