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Peptide record

TPDB13736

Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB13736
Antibacterial Anticancer Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP pep-lab Peptipedia AntiCP 2.0 iACP-DRLF Antifungipept APD_complete APD_hemolytic
standard
No
A 37-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GIFSLVKGAAKLAGKGLAKEGGKFGLELIACKIAKQC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C169H289N45O44S2
RNDHMPTWY
GK
3719.55
10.18
7
2
17
+5
-0.21
0.451
108.38
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
0.03
4
Residue Composition
number
6
A
0
R
0
N
0
D
2
C
2
E
1
Q
7
G
0
H
3
I
5
L
7
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 2 E: 2 Q: 1 G: 7 H: 0 I: 3 L: 5 K: 7 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
37 reviewed residue count
C169H289N45O44S2 sequence-only estimate (linear, free termini)
3719.55 sequence-only estimate (linear, free termini)
10.18 sequence-only estimate (linear, free termini)
+5 sequence-only estimate (linear, free termini)
-0.21 sequence-only estimate (linear, free termini)
0.451 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP APD_complete APD_hemolytic Antifungipept
Evidence 2 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.