Back to search

Peptide record

TPDB13720

Antibacterial Antifungal Toxicity standard
37 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB13720
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept
standard
No
A 37-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from AntiBP3, Peptipedia, and Antifungipept, with an available 3D structural model.
Sequence
GFGGGRGGFGGGRGGFGGGGIGGGGFGGGYGGGKIKG
Physicochemical Analysis
C133H195N45O39
ANDCEQHLMPSTWV
G
3048.29
11.51
4
0
7
+4
-2.22
-0.224
21.08
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
48.88
1
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
26
G
0
H
2
I
0
L
2
K
0
M
4
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 26 H: 0 I: 2 L: 0 K: 2 M: 0 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
37
C133H195N45O39
3048.29
11.51
+4
-2.22
-0.224
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.5-1 µM

Target

M. luteus A270

Source & Reference

NA

Other

Active against Gram+ bacteria M. luteus A270 (MIC 0.5-1 uM), Gram- E. coli SBS 363 (MIC 9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A
Evidence 2 Activity

Activity

MIC
Antibacterial
9-16 µM

Target

Escherichia coli SBS 363

Source & Reference

NA

Other

Active against Gram+ bacteria M. luteus A270 (MIC 0.5-1 uM), Gram- E. coli SBS 363 (MIC 9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A. niger (3-6 uM), and yeast C. albica
Evidence 3 Activity

Activity

MIC
Antibacterial
0.01-0.3 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

NA

Other

gainst Gram+ bacteria M. luteus A270 (MIC 0.5-1 uM), Gram- E. coli SBS 363 (MIC 9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A. niger (3-6 uM), and yeast C. albicans MDMS (MIC 1.5-3 uM). The peptide was not
Evidence 4 Activity

Activity

MIC
Antibacterial
1.5-3 µM

Target

Candida albicans MDMS

Source & Reference

NA

Other

9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A. niger (3-6 uM), and yeast C. albicans MDMS (MIC 1.5-3 uM). The peptide was not hemo-lytic at 16 uM. 7/2021
Evidence 5 Activity

Activity

MIC
Antifungal
0.5-1 µM

Target

M. luteus A270

Source & Reference

Antifungipept

Other

Active against Gram+ bacteria M. luteus A270 (MIC 0.5-1 uM), Gram- E. coli SBS 363 (MIC 9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A
Evidence 6 Activity

Activity

MIC
Antifungal
9-16 µM

Target

Escherichia coli SBS 363

Source & Reference

Antifungipept

Other

Active against Gram+ bacteria M. luteus A270 (MIC 0.5-1 uM), Gram- E. coli SBS 363 (MIC 9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A. niger (3-6 uM), and yeast C. albica
Evidence 7 Activity

Activity

MIC
Antifungal
0.01-0.3 µM

Target

Pseudomonas aeruginosa ATCC 27853

Source & Reference

Antifungipept

Other

gainst Gram+ bacteria M. luteus A270 (MIC 0.5-1 uM), Gram- E. coli SBS 363 (MIC 9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A. niger (3-6 uM), and yeast C. albicans MDMS (MIC 1.5-3 uM). The peptide was not
Evidence 8 Activity

Activity

MIC
Antifungal
1.5-3 µM

Target

Candida albicans MDMS

Source & Reference

Antifungipept

Other

9-16 uM), P. aeruginosa ATCC 27853 (MIC 0.01-0.3 uM), Fungi A. niger (3-6 uM), and yeast C. albicans MDMS (MIC 1.5-3 uM). The peptide was not hemo-lytic at 16 uM. 7/2021
Evidence 9 Activity

Activity

0% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
0% Hemolysis | 50 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Serrulin: A Glycine-Rich Bioactive Peptide from the Hemolymph of the Yellow Tityus serrulatus Scorpion. | Toxins (Basel) | 2019