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Peptide record

TPDB13709

Antibacterial Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB13709
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 36-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GRFRRLRKKTRKRLKKIGKVLKWIKKIVGSIPLGCG
Physicochemical Analysis
C193H346N64O39S1
ANDEQHMY
K
4219.34
12.72
15
0
12
+15
7.98
-0.589
102.78
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
130.35
3
Residue Composition
number
0
A
6
R
0
N
0
D
1
C
0
E
0
Q
5
G
0
H
4
I
4
L
9
K
0
M
1
F
1
P
1
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 5 H: 0 I: 4 L: 4 K: 9 M: 0 F: 1 P: 1 S: 1 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
36
C193H346N64O39S1
4219.34
12.72
+15
7.98
-0.589
Evidence Records 3 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 128 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of the antibacterial peptide PMAP-36 and its analogues. | Microb Pathog | 2019
Evidence 2 Activity

Activity

27% Hemolysis
Toxicity
512 µg/mL
Hemolytic Cytotoxic
27% Hemolysis | 512 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial activity of the antibacterial peptide PMAP-36 and its analogues. | Microb Pathog | 2019
Evidence 3 Activity

Activity

24% Killing
Toxicity
512 µg/mL
Cytotoxic
24% Killing | 512 | µg/mL | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Antimicrobial activity of the antibacterial peptide PMAP-36 and its analogues. | Microb Pathog | 2019