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Peptide record

TPDB13693

Antibacterial Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB13693
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLRRLLRKIRGRWKGGGRGGRLCYCRRRFCVCVGR
Physicochemical Analysis
C175H303N71O37S4
ANDEQHMPST
R
4122.02
12.33
13
0
10
+13
3.68
-0.623
72.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
7240
175.64
5
Residue Composition
number
0
A
11
R
0
N
0
D
4
C
0
E
0
Q
8
G
0
H
1
I
4
L
2
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 11 N: 0 D: 0 C: 4 E: 0 Q: 0 G: 8 H: 0 I: 1 L: 4 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
35
C175H303N71O37S4
4122.02
12.33
+13
3.68
-0.623
Evidence Records 1 records
Evidence 1 Activity

Activity

45% Killing
Toxicity
100 µg/mL
Cytotoxic
45% Killing | 100 | µg/mL | target cell: Intestinal Porcine Epithelial Cells IPEC-J2

Target

Intestinal Porcine Epithelial Cells IPEC-J2

Source & Reference

NA
DBAASP
The Addition of a Synthetic LPS-Targeting Domain Improves Serum Stability While Maintaining Antimicrobial, Antibiofilm, and Cell Stimulating Properties of an Antimicrobial Peptide. | Biomolecules | 2020