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Peptide record

TPDB13691

Antibacterial Toxicity standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB13691
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 35-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
KWKVLKKKIKMLRNRINGLVKAGPALKVKLQALAL
Physicochemical Analysis
C185H332N54O39S1
DCEHFSTY
K
3969.07
12.48
11
0
18
+11
5.33
-0.017
136.57
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
5500
138.57
3
Residue Composition
number
4
A
2
R
2
N
0
D
0
C
0
E
1
Q
2
G
0
H
2
I
7
L
9
K
1
M
0
F
1
P
0
S
0
T
1
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 7 K: 9 M: 1 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 3
Chemical Descriptors
35
C185H332N54O39S1
3969.07
12.48
+11
5.33
-0.017
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
>>250 µM
Hemolytic Cytotoxic
50% Hemolysis | >>250 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Anti-antimicrobial Peptides: Folding-Mediated Host Defense Antagonists | J Biol Chem | 2013