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Peptide record

TPDB13688

Antibacterial Anticancer Antifungal Antiparasitic standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB13688
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia ACP740 _ACP240 AntiCP 2.0 iACP-DRLF Antifungipept
standard
No
A 35-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
GGLKKLGKKLEGVGKRVFKASEKALPVLTGYKAIG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C168H290N46O43
NDCQHMW
K
3642.43
10.77
9
2
14
+7
0.64
-0.160
100.29
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
0.41
3
Residue Composition
number
3
A
1
R
0
N
0
D
0
C
2
E
0
Q
7
G
0
H
1
I
5
L
8
K
0
M
1
F
1
P
1
S
1
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 7 H: 0 I: 1 L: 5 K: 8 M: 0 F: 1 P: 1 S: 1 T: 1 W: 0 Y: 1 V: 3
Chemical Descriptors
35 reviewed residue count
C168H290N46O43 sequence-only estimate (linear, free termini)
3642.43 sequence-only estimate (linear, free termini)
10.77 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
0.64 sequence-only estimate (linear, free termini)
-0.160 sequence-only estimate (linear, free termini)
Evidence Records 3 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Activity not tested. Updated 7/2021
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP DRAMP Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Activity not tested. Updated 7/2021
Evidence 3 Activity

Activity

Antiparasitic

Source & Reference

DRAMP

Other

Activity not tested. Updated 7/2021