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Peptide record

TPDB13672

Antibacterial Anticancer Antifungal Antiparasitic standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB13672
Antibacterial Anticancer Antifungal Antiparasitic
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP DRAMP Peptipedia AntiCP 2.0 iACP-DRLF
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
APRWKFGKRLEKLGRNVFRAAKKALPVIAGYKAL
Physicochemical Analysis
C181H298N54O39
DCQHMST
AK
3854.70
12.03
10
1
17
+9
4.07
-0.309
92.06
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
6990
181.34
2
Residue Composition
number
6
A
4
R
1
N
0
D
0
C
1
E
0
Q
3
G
0
H
1
I
4
L
6
K
0
M
2
F
2
P
0
S
0
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 6 R: 4 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 4 K: 6 M: 0 F: 2 P: 2 S: 0 T: 0 W: 1 Y: 1 V: 2
Chemical Descriptors
34
C181H298N54O39
3854.70
12.03
+9
4.07
-0.309
Evidence Records 12 records
Evidence 1 Activity

Activity

IC50
Antibacterial
12.4 µM

Target

P. falciparum 3D7

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class. DRAMP antibacterial activity supported by MIC records against bacterial target organisms.
inhibited P. falciparum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75
Evidence 2 Activity

Activity

MIC
Antibacterial
30 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

inhibited P. falciparum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 3 Activity

Activity

MIC
Antibacterial
3.75 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

rum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 4 Activity

Activity

MIC
Antibacterial
3.75 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

iton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 5 Activity

Activity

IC50
Antifungal
12.4 µM

Target

P. falciparum 3D7

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class. DRAMP antifungal activity supported by activity records against fungal target organisms.
inhibited P. falciparum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75
Evidence 6 Activity

Activity

MIC
Antifungal
30 µM

Target

Staphylococcus aureus

Source & Reference

dbAMP DRAMP

Other

inhibited P. falciparum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 7 Activity

Activity

MIC
Antifungal
3.75 µM

Target

B. subtilis

Source & Reference

dbAMP DRAMP

Other

rum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 8 Activity

Activity

MIC
Antifungal
3.75 µM

Target

Escherichia coli

Source & Reference

dbAMP DRAMP

Other

iton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 9 Activity

Activity

IC50
Antiparasitic
12.4 µM

Target

P. falciparum 3D7

Source & Reference

DRAMP

Other

Source Activity Label Source Definition
Antiparasitic
DRAMP antiparasitic activity supported by activity records against parasitic targets.
inhibited P. falciparum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75
Evidence 10 Activity

Activity

MIC
Antiparasitic
30 µM

Target

Staphylococcus aureus

Source & Reference

DRAMP

Other

inhibited P. falciparum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 11 Activity

Activity

MIC
Antiparasitic
3.75 µM

Target

B. subtilis

Source & Reference

DRAMP

Other

rum 3D7 (IC50 12.4 uM). In addiiton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).
Evidence 12 Activity

Activity

MIC
Antiparasitic
3.75 µM

Target

Escherichia coli

Source & Reference

DRAMP

Other

iton, it inhibited bacterial growth S. aureus (MIC 30 uM), B. subtilis (MIC 3.75 uM), and E. coli (MIC 3.75 uM).