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Peptide record

TPDB13671

Antibacterial Anticancer Antifungal Antiviral Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB13671
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia CAFPdb dbAMP dbAMP 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, CAFPdb, and other sources, with an available 3D structural model.
Sequence
KCAGSIAWAIGSGLFGGAKLIKIKKYIAELGGLQ
Physicochemical Analysis
C161H265N41O41S1
RNDHMPTV
G
3463.18
10.20
5
1
17
+4
-0.92
0.556
117.94
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
6990
201.84
5
Residue Composition
number
5
A
0
R
0
N
0
D
1
C
1
E
1
Q
7
G
0
H
5
I
4
L
5
K
0
M
1
F
0
P
2
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 5 R: 0 N: 0 D: 0 C: 1 E: 1 Q: 1 G: 7 H: 0 I: 5 L: 4 K: 5 M: 0 F: 1 P: 0 S: 2 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
34
C161H265N41O41S1
3463.18
10.20
+4
-0.92
0.556
Evidence Records 3 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
438.00 µg/mL
Cytotoxic
50% Cytotoxicity | 438.00 | µg/mL | target cell: Vero E6 cells

Target

Vero E6 cells

Source & Reference

NA
DBAASP
New Antibacterial Peptides from the Freshwater Mollusk Pomacea poeyana (Pilsbry, 1927). | Biomolecules | 2020
Evidence 2 Activity

Activity

30% Cytotoxicity
Toxicity
100 µg/mL
Cytotoxic
30% Cytotoxicity | 100 | µg/mL | target cell: Human primary macrophages

Target

Human primary macrophages

Source & Reference

NA
DBAASP
New Antibacterial Peptides from the Freshwater Mollusk Pomacea poeyana (Pilsbry, 1927). | Biomolecules | 2020
Evidence 3 Activity

Activity

Toxicity
Hemolytic Cytotoxic
Hemolytic_activity: Not available | Cytotoxicity: Vero E6: 50% Cytotoxicity=438 µM

Target

erythrocytes

Source & Reference

NA
DRAMP
Biomolecules. 2020 Oct 23 10(11):1473.