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Peptide record

TPDB13670

Antibacterial Anticancer Antiparasitic Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB13670
Antibacterial Anticancer Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Anticancer, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and dbAMP 3.0, with an available 3D structural model.
Sequence
AMAYLAKDNLGEKITEVITILLNRLTDRLEKYAG
Physicochemical Analysis
C171H287N45O52S1
CQHFPSW
L
3837.49
7.08
5
5
17
+0
7.38
-0.032
123.53
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
2980
77.65
7
Residue Composition
number
4
A
2
R
2
N
2
D
0
C
3
E
0
Q
2
G
0
H
3
I
6
L
3
K
1
M
0
F
0
P
0
S
3
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 4 R: 2 N: 2 D: 2 C: 0 E: 3 Q: 0 G: 2 H: 0 I: 3 L: 6 K: 3 M: 1 F: 0 P: 0 S: 0 T: 3 W: 0 Y: 2 V: 1
Chemical Descriptors
34
C171H287N45O52S1
3837.49
7.08
+0
7.38
-0.032
Evidence Records 5 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
8-16 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 8-16 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. | PLoS Negl Trop Dis | 2013
Evidence 2 Activity

Activity

1.8% Hemolysis
Toxicity
32 µg/mL
Hemolytic Cytotoxic
1.8% Hemolysis | 32 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. | PLoS Negl Trop Dis | 2013
Evidence 3 Activity

Activity

2.6% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
2.6% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. | PLoS Negl Trop Dis | 2013
Evidence 4 Activity

Activity

5.4% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
5.4% Hemolysis | 128 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. | PLoS Negl Trop Dis | 2013
Evidence 5 Activity

Activity

11.4% Hemolysis
Toxicity
256 µg/mL
Hemolytic Cytotoxic
11.4% Hemolysis | 256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP