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Peptide record

TPDB13667

Antibacterial Antifungal Hemolysis Toxicity standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB13667
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP APD_complete APD_hemolytic Hemolytic2
standard
No
A 34-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, AFP-GFuse, and other sources, with an available 3D structural model.
Sequence
GILDKLKEFGISAARGVAQSLLNTTASCKLAKTC
Physicochemical Analysis
C152H263N43O47S2
HMPWY
AL
3509.14
9.71
5
2
14
+3
4.05
0.271
103.53
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.56
10
Residue Composition
number
5
A
1
R
1
N
1
D
2
C
1
E
1
Q
3
G
0
H
2
I
5
L
4
K
0
M
1
F
0
P
3
S
3
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 5 R: 1 N: 1 D: 1 C: 2 E: 1 Q: 1 G: 3 H: 0 I: 2 L: 5 K: 4 M: 0 F: 1 P: 0 S: 3 T: 3 W: 0 Y: 0 V: 1
Chemical Descriptors
34
C152H263N43O47S2
3509.14
9.71
+3
4.05
0.271
Evidence Records 9 records
Evidence 1 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
ve bacteria: R. rhodochrous X15 (IS) (MIC 2.3 uM), B. licheniformis X39 (IS) (MIC 75 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 37.5 uM), S. aureus ATCC 25923(MIC 37.5 uM), E.coli ATCC 25922
Evidence 2 Activity

Activity

MIC
Antibacterial
37.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP

Other

s X39 (IS) (MIC 75 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 37.5 uM), S. aureus ATCC 25923(MIC 37.5 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 1105
Evidence 3 Activity

Activity

MIC
Antibacterial
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP

Other

981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 37.5 uM), S. aureus ATCC 25923(MIC 37.5 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 4 Activity

Activity

MIC
Antibacterial
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP

Other

24 (IS)(MIC >150 uM), P. faecalis X29 (IS)(MIC 2.3 uM), S. rubidaea X01 (IS)(MIC 2.3 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 9 uM). IS: Isolated strain.
Evidence 5 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Enterococcus faecalis 981

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
ve bacteria: R. rhodochrous X15 (IS) (MIC 2.3 uM), B. licheniformis X39 (IS) (MIC 75 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 37.5 uM), S. aureus ATCC 25923(MIC 37.5 uM), E.coli ATCC 25922
Evidence 6 Activity

Activity

MIC
Antifungal
37.5 µM

Target

Staphylococcus aureus ATCC 25923

Source & Reference

dbAMP CAFPdb Antifungipept

Other

s X39 (IS) (MIC 75 uM), E. faecalis 981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 37.5 uM), S. aureus ATCC 25923(MIC 37.5 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 1105
Evidence 7 Activity

Activity

MIC
Antifungal
150 µM

Target

E.coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

981 (MIC 37.5 uM), S. carnosus KHS (IS)(MIC 37.5 uM), S. aureus ATCC 25923(MIC 37.5 uM), E.coli ATCC 25922 (MIC 150 uM), P.aeruginosa CGMCC 1.50 (MIC >150 uM), P.aeruginosa 11053 (IS)(MIC >150 uM), K.pneumonia
Evidence 8 Activity

Activity

MIC
Antifungal
>150 µM

Target

C.albicans ATCC 10231

Source & Reference

dbAMP CAFPdb Antifungipept

Other

24 (IS)(MIC >150 uM), P. faecalis X29 (IS)(MIC 2.3 uM), S. rubidaea X01 (IS)(MIC 2.3 uM), C.albicans ATCC 10231 (MIC >150 uM), Slime mold 090223 (IS) (MIC 9 uM). IS: Isolated strain.
Evidence 9 Hemolysis

Source & Reference

APD_complete APD_hemolytic
APD_complete APD_hemolytic

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation. APD_hemolytic APD hemolytic peptide annotation.