Peptide record

TPDB13651

Antibacterial Toxicity standard
33 amino acids
Basic Information
3D PDB MODEL
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TPDB13651
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 Peptipedia
standard
No
A 33-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
RPLNFKMLRFWGQQQCRRPLYCRRRWSHPQFEK
Physicochemical Analysis
C196H299N65O43S3
ADITV
R
4350.12
12.02
10
1
10
+8
4.44
-1.391
35.45
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12615
289.99
9
Residue Composition
number
0
A
7
R
1
N
0
D
2
C
1
E
4
Q
1
G
1
H
0
I
3
L
2
K
1
M
3
F
3
P
1
S
0
T
2
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 7 N: 1 D: 0 C: 2 E: 1 Q: 4 G: 1 H: 1 I: 0 L: 3 K: 2 M: 1 F: 3 P: 3 S: 1 T: 0 W: 2 Y: 1 V: 0
Chemical Descriptors
33
C196H299N65O43S3
4350.12
12.02
+8
4.44
-1.391
Evidence Records 2 records
Evidence 1 Activity

Activity

1.75% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
1.75% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020
Evidence 2 Activity

Activity

3.51% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
3.51% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Potent Chimeric Antimicrobial Derivatives of the Medicago truncatula NCR247 Symbiotic Peptide. | Front Microbiol | 2020