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Peptide record

TPDB13639

Antibacterial Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB13639
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
AntiBP3 dbAMP Peptipedia
standard
No
A 32-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from AntiBP3, dbAMP, and Peptipedia, with an available 3D structural model.
Sequence
ATCYCRRGRCATRESLSGVCRISGRLYRLCCR
Physicochemical Analysis
C147H254N56O42S6
NDQHKMFPW
R
3670.34
9.76
8
1
9
+7
3.62
-0.263
64.06
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
3355
91.41
13
Residue Composition
number
2
A
8
R
0
N
0
D
6
C
1
E
0
Q
3
G
0
H
1
I
3
L
0
K
0
M
0
F
0
P
3
S
2
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 2 R: 8 N: 0 D: 0 C: 6 E: 1 Q: 0 G: 3 H: 0 I: 1 L: 3 K: 0 M: 0 F: 0 P: 0 S: 3 T: 2 W: 0 Y: 2 V: 1
Chemical Descriptors
32
C147H254N56O42S6
3670.34
9.76
+7
3.62
-0.263
Evidence Records 1 records
Evidence 1 Activity

Activity

0.7% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
0.7% Hemolysis | 100 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Design of a potent antibiotic peptide based on the active region of human defensin 5. | J Med Chem | 2015