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Peptide record

TPDB13627

Antibacterial Anticancer Antiparasitic Toxicity standard
32 amino acids
Basic Information
3D PDB MODEL
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TPDB13627
Antibacterial Anticancer Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia dbAMP 3.0
standard
No
A 32-aa standard natural multi-activity (Antibacterial, Anticancer, Antiparasitic, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and dbAMP 3.0, with an available 3D structural model.
Sequence
IRKYLEEDNLGEKLAAVVSIYVKRLNKRLDMR
Physicochemical Analysis
C170H290N50O48S1
CQHFPTW
L
3834.54
10.12
8
5
15
+3
11.04
-0.494
118.75
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
2980
77.71
5
Residue Composition
number
2
A
4
R
2
N
2
D
0
C
3
E
0
Q
1
G
0
H
2
I
5
L
4
K
1
M
0
F
0
P
1
S
0
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 2 R: 4 N: 2 D: 2 C: 0 E: 3 Q: 0 G: 1 H: 0 I: 2 L: 5 K: 4 M: 1 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 2 V: 3
Chemical Descriptors
32
C170H290N50O48S1
3834.54
10.12
+3
11.04
-0.494
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
8-256 µg/mL
Hemolytic Cytotoxic
0% Hemolysis | 8-256 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation. | PLoS Negl Trop Dis | 2013