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Peptide record

TPDB13612

Antibacterial standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB13612
Antibacterial
Anti-infective peptides
AntiBP3 Peptipedia
standard
No
A 31-aa standard natural antibacterial peptide sequence curated from AntiBP3 and Peptipedia, with an available 3D structural model.
Sequence
GLLDIIKTTGKDFAVKILDNLKCKLAGGCPP
Physicochemical Analysis
C146H249N37O41S2
REQHMSWY
LK
3242.93
9.02
5
3
12
+2
4.67
0.271
116.45
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
125
3.85
5
Residue Composition
number
2
A
0
R
1
N
3
D
2
C
0
E
0
Q
4
G
0
H
3
I
5
L
5
K
0
M
1
F
2
P
0
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 3 C: 2 E: 0 Q: 0 G: 4 H: 0 I: 3 L: 5 K: 5 M: 0 F: 1 P: 2 S: 0 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
31
C146H249N37O41S2
3242.93
9.02
+2
4.67
0.271
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
>2560 µg/mL

Target

S.aureus ATCC 6538P

Source & Reference

NA

Other

Active against Gram+ S.aureus ATCC 6538P (MIC>2560 ug/ml), S. pyogenes (MIC 79 ug/ml), Gram- P.aeruginosa ATCC 10148 (MIC>2560 ug/ml), E. coli ATCC
Evidence 2 Activity

Activity

MIC
Antibacterial
79 µg/mL

Target

Streptococcus pyogenes

Source & Reference

NA

Other

Active against Gram+ S.aureus ATCC 6538P (MIC>2560 ug/ml), S. pyogenes (MIC 79 ug/ml), Gram- P.aeruginosa ATCC 10148 (MIC>2560 ug/ml), E. coli ATCC 9723H or 25922 or MDR CPO-N
Evidence 3 Activity

Activity

MIC
Antibacterial
>2560 µg/mL

Target

P.aeruginosa ATCC 10148

Source & Reference

NA

Other

ive against Gram+ S.aureus ATCC 6538P (MIC>2560 ug/ml), S. pyogenes (MIC 79 ug/ml), Gram- P.aeruginosa ATCC 10148 (MIC>2560 ug/ml), E. coli ATCC 9723H or 25922 or MDR CPO-NDM (MIC 10-39 ug/ml). Updated 6/2024
Evidence 4 Activity

Activity

MIC
Antibacterial
10-39 µg/mL

Target

Escherichia coli ATCC 9723H or 25922 or MDR CPO-NDM

Source & Reference

NA

Other

>2560 ug/ml), S. pyogenes (MIC 79 ug/ml), Gram- P.aeruginosa ATCC 10148 (MIC>2560 ug/ml), E. coli ATCC 9723H or 25922 or MDR CPO-NDM (MIC 10-39 ug/ml). Updated 6/2024