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Peptide record

TPDB13603

Antibacterial Anticancer Antifungal Antiparasitic Toxicity standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB13603
Antibacterial Anticancer Antifungal Antiparasitic Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia Antifungipept ToxinPred 3.0
standard
No
A 30-aa standard-residue multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
FVYGNGVTSILVQAQFLVNGQRRFFYTPDK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C162H242N42O43
CEHMW
FV
3465.96
10.08
3
1
14
+2
1.18
0.013
81.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
2980
0.86
10
Residue Composition
number
1
A
2
R
2
N
1
D
0
C
0
E
3
Q
3
G
0
H
1
I
2
L
1
K
0
M
4
F
1
P
1
S
2
T
0
W
2
Y
4
V
Amino Acid Distribution
A: 1 R: 2 N: 2 D: 1 C: 0 E: 0 Q: 3 G: 3 H: 0 I: 1 L: 2 K: 1 M: 0 F: 4 P: 1 S: 1 T: 2 W: 0 Y: 2 V: 4
Chemical Descriptors
30 reviewed residue count
C162H242N42O43 sequence-only estimate (linear, free termini)
3465.96 sequence-only estimate (linear, free termini)
10.08 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
1.18 sequence-only estimate (linear, free termini)
0.013 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Murine macrophages

Target

Murine macrophages

Source & Reference

NA
DBAASP
Antimycobacterial activity of bacteriocins and their complexes with liposomes. | J Antimicrob Chemother | 2007