Peptide record

TPDB13601

CEN1 HC Centrocin 1a heavy chain Antibacterial Anticancer Antifungal Antiparasitic Antiviral standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB13601
CEN1 HC Centrocin 1a heavy chain
Antibacterial Anticancer Antifungal Antiparasitic Antiviral
Anti-infective peptides Cancer-related peptides
AntiBP3 dbAMP Peptipedia Antifungipept CAFPdb DBAASP
standard
No
A 30-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, Peptipedia, and other sources, with an available 3D structural model.
Sequence
GWFKKTFHKVSHAVKSGIHAGQRGCSALGF
Physicochemical Analysis
C148H225N45O36S1
NDEMPY
G
3242.75
10.98
8
0
11
+5
2.09
-0.207
55.33
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
5500
169.61
6
Residue Composition
number
3
A
1
R
0
N
0
D
1
C
0
E
1
Q
5
G
3
H
1
I
1
L
4
K
0
M
3
F
0
P
3
S
1
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 5 H: 3 I: 1 L: 1 K: 4 M: 0 F: 3 P: 0 S: 3 T: 1 W: 1 Y: 0 V: 2
Chemical Descriptors
30
C148H225N45O36S1
3242.75
10.98
+5
2.09
-0.207
Evidence Records 17 records
Evidence 1 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aur
Evidence 2 Activity

Activity

MIC
Antibacterial
1.3 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 3 Activity

Activity

MIC
Antibacterial
1.3 µM

Target

C. glutamicum ATCC 13032

Source & Reference

dbAMP

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 4 Activity

Activity

MIC
Antibacterial
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

dbAMP

Other

.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 5 Activity

Activity

MIC
Antifungal
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aur
Evidence 6 Activity

Activity

MIC
Antifungal
1.3 µM

Target

Escherichia coli ATCC 25922

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 7 Activity

Activity

MIC
Antifungal
1.3 µM

Target

C. glutamicum ATCC 13032

Source & Reference

dbAMP CAFPdb Antifungipept

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 8 Activity

Activity

MIC
Antifungal
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

dbAMP CAFPdb Antifungipept

Other

.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 9 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

NA

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aur
Evidence 10 Activity

Activity

MIC
Antiparasitic
1.3 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 11 Activity

Activity

MIC
Antiparasitic
1.3 µM

Target

C. glutamicum ATCC 13032

Source & Reference

NA

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 12 Activity

Activity

MIC
Antiparasitic
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

NA

Other

.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 13 Activity

Activity

MIC
Antiviral
2.5 µM

Target

L. anguillarum serotype O2

Source & Reference

NA

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aur
Evidence 14 Activity

Activity

MIC
Antiviral
1.3 µM

Target

Escherichia coli ATCC 25922

Source & Reference

NA

Other

Active against Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The m
Evidence 15 Activity

Activity

MIC
Antiviral
1.3 µM

Target

C. glutamicum ATCC 13032

Source & Reference

NA

Other

nst Gram- L. anguillarum serotype O2 (MIC 2.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set
Evidence 16 Activity

Activity

MIC
Antiviral
2.5 µM

Target

Staphylococcus aureus ATCC 9144

Source & Reference

NA

Other

.5 uM), E. coli ATCC 25922 (MIC 1.3 uM), Gram+ C. glutamicum ATCC 13032 (MIC 1.3 uM), and S. aureus ATCC 9144 (MIC 2.5 uM). The minimal inhibitory concentration (MIC) was set at the lowest concentration of peptid
Evidence 17 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP