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Peptide record

TPDB13580

Antibacterial Anticancer Antifungal Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB13580
Antibacterial Anticancer Antifungal Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 dbAMP DRAMP Peptipedia AFP-GFuse Antifungipept CAFPdb APD_complete PD_Hemolysis ToxinPred 3.0
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, dbAMP, DRAMP, and other sources, with an available 3D structural model.
Sequence
KRIRFFERIRDRLRDLGNRIKNRIRDFFS
Physicochemical Analysis
C168H278N60O41
ACQHMPTWYV
R
3794.43
12.31
11
4
10
+7
9.08
-1.162
80.69
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
9
R
2
N
3
D
0
C
1
E
0
Q
1
G
0
H
4
I
2
L
2
K
0
M
4
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 2 D: 3 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 4 L: 2 K: 2 M: 0 F: 4 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
29
C168H278N60O41
3794.43
12.31
+7
9.08
-1.162
Evidence Records 4 records
Evidence 1 Activity

Activity

8% Hemolysis
Toxicity
31.25 µg/mL
Hemolytic Cytotoxic
8% Hemolysis | 31.25 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 2 Activity

Activity

10% Hemolysis
Toxicity
62.5 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 62.5 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 3 Activity

Activity

12% Hemolysis
Toxicity
125 µg/mL
Hemolytic Cytotoxic
12% Hemolysis | 125 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Cathelicidins in the Tasmanian devil (Sarcophilus harrisii). | Sci Rep | 2016
Evidence 4 Hemolysis

Source & Reference

APD_complete PD_Hemolysis
APD_complete PD_Hemolysis

Other

Source Activity Label Source Definition
Hemolysis
APD_complete APD-derived hemolytic peptide annotation.