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Peptide record

TPDB13578

Antibacterial Anticancer Hemolysis Toxicity standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB13578
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia PD_Hemolysis
standard
No
A 29-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from AntiBP3, Peptipedia, and PD_Hemolysis, with an available 3D structural model.
Sequence
LRRLRRRLRRLRRRWRRRLRRLRRRLRRL
Physicochemical Analysis
C179H340N90O30
ANDCEQGHIKMFPSTYV
R
4233.25
13.68
20
0
9
+20
9.87
-2.086
107.59
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
129.92
0
Residue Composition
number
0
A
20
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 20 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
29
C179H340N90O30
4233.25
13.68
+20
9.87
-2.086
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
10% Hemolysis | 64 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism. | J Med Chem | 2017
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis