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Peptide record

TPDB13573

Antibacterial Anticancer Antifungal Antiviral Toxicity standard
28 amino acids
Basic Information
3D PDB MODEL
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TPDB13573
Antibacterial Anticancer Antifungal Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
AntiBP3 Peptipedia Antifungipept CAFPdb dbAMP AI4AVP dbAMP 3.0
standard
No
A 28-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from AntiBP3, Peptipedia, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FLPIIVFQFLGKIIHHVGNFVHGFSHVF
Physicochemical Analysis
C163H233N39O32
ARDCEMTWY
F
3250.89
10.10
5
0
16
+1
-2.42
1.139
125.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
1
Q
3
G
4
H
4
I
2
L
1
K
0
M
6
F
1
P
1
S
0
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 4 I: 4 L: 2 K: 1 M: 0 F: 6 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 4
Chemical Descriptors
28
C163H233N39O32
3250.89
10.10
+1
-2.42
1.139
Evidence Records 4 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
200 µg/mL
Cytotoxic
50% Cell death | 200 | µg/mL | target cell: Vero cells

Target

Vero cells

Source & Reference

NA
DBAASP
Linear Antimicrobial Peptides With Activity Against Herpes Simplex Virus 1 and Aichi Virus | Biopolymers | 2017
Evidence 2 Activity

Activity

<10% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<10% Hemolysis | 200 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. | Sci Rep | 2016
Evidence 3 Activity

Activity

LC50
Toxicity
>600 µM
Cytotoxic
LC50 | >600 | µM | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. | Sci Rep | 2016
Evidence 4 Activity

Activity

LC50
Toxicity
>600 µM
Cytotoxic
LC50 | >600 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. | Sci Rep | 2016